caa a22 4500 605518467 CHVBK 20210128100725.0 cr unu---uuuuu 210128e20150101xx s 000 0 eng 10.1007/s10559-015-9695-z doi (NATIONALLICENCE)springer-10.1007/s10559-015-9695-z Using Em-Algorithm for Gene Classification [Elektronische Daten] [I. Sergienko, A. Gupal, A. Ostrovskiy] The EM algorithm is considered for the problem of separation of distribution mixtures described by Markov chains, together with the related weighted likelihood maximization problem. Auxiliary algorithms are proposed to select the initial approximation and optimal number of mixture components, as well as a method to approximate the distribution mixture with given data using support vector machines. The results are applied to gene fragment classification. Springer Science+Business Media New York, 2015 Markov chain nationallicence classification nationallicence gene nationallicence bioinformatics nationallicence nucleotide nationallicence exon nationallicence intron nationallicence likelihood nationallicence Sergienko I. V. M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine aut Gupal A. V. M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine aut Ostrovskiy A. V. M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine aut Cybernetics and Systems Analysis Springer US; http://www.springer-ny.com 51/1(2015-01-01), 41-50 1060-0396 51:1<41 2015 51 10559 https://doi.org/10.1007/s10559-015-9695-z text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10559-015-9695-z text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sergienko I. V. M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Gupal A. V. M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine aut NATIONALLICENCE 700 1- Ostrovskiy A. V. M. Glushkov Institute of Cybernetics, National Academy of Sciences of Ukraine, Kyiv, Ukraine aut NATIONALLICENCE 773 0- Cybernetics and Systems Analysis Springer US; http://www.springer-ny.com 51/1(2015-01-01), 41-50 1060-0396 51:1<41 2015 51 10559