Bone's Material Constituents and their Contribution to Bone Strength in Health, Disease, and Treatment

Verfasser / Beitragende:
[Y. Bala, E. Seeman]
Ort, Verlag, Jahr:
2015
Enthalten in:
Calcified Tissue International, 97/3(2015-09-01), 308-326
Format:
Artikel (online)
ID: 605520607
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024 7 0 |a 10.1007/s00223-015-9971-y  |2 doi 
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245 0 0 |a Bone's Material Constituents and their Contribution to Bone Strength in Health, Disease, and Treatment  |h [Elektronische Daten]  |c [Y. Bala, E. Seeman] 
520 3 |a Type 1 collagen matrix volume, its degree of completeness of its mineralization, the extent of collagen crosslinking and water content, and the non-collagenous proteins like osteopontin and osteocalcin comprise the main constituents of bone's material composition. Each influences material strength and change in different ways during advancing age, health, disease, and drug therapy. These traits are not quantifiable using bone densitometry and their plurality is better captured by the term bone ‘qualities' than ‘quality'. These qualities are the subject of this manuscript. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a Bone water  |2 nationallicence 
690 7 |a Collagen  |2 nationallicence 
690 7 |a Mineralization  |2 nationallicence 
690 7 |a Osteopontin  |2 nationallicence 
690 7 |a Osteocalcin  |2 nationallicence 
690 7 |a Pentosidine  |2 nationallicence 
690 7 |a Qualities of bone  |2 nationallicence 
700 1 |a Bala  |D Y.  |u Laboratoire Vibrations Acoustique, Institut National des Sciences Appliquées de Lyon, Campus LyonTech la Doua, Villeurbanne, France  |4 aut 
700 1 |a Seeman  |D E.  |u Departments of Endocrinology and Medicine, Centaur Wing, Repatriation Campus, Austin Health, University of Melbourne, Waterdale rd, Heidelberg, 3081, Melbourne, Australia  |4 aut 
773 0 |t Calcified Tissue International  |d Springer US; http://www.springer-ny.com  |g 97/3(2015-09-01), 308-326  |x 0171-967X  |q 97:3<308  |1 2015  |2 97  |o 223 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bala  |D Y.  |u Laboratoire Vibrations Acoustique, Institut National des Sciences Appliquées de Lyon, Campus LyonTech la Doua, Villeurbanne, France  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Seeman  |D E.  |u Departments of Endocrinology and Medicine, Centaur Wing, Repatriation Campus, Austin Health, University of Melbourne, Waterdale rd, Heidelberg, 3081, Melbourne, Australia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Calcified Tissue International  |d Springer US; http://www.springer-ny.com  |g 97/3(2015-09-01), 308-326  |x 0171-967X  |q 97:3<308  |1 2015  |2 97  |o 223