caa a22 4500 605520607 CHVBK 20210128100736.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s00223-015-9971-y doi (NATIONALLICENCE)springer-10.1007/s00223-015-9971-y Bone's Material Constituents and their Contribution to Bone Strength in Health, Disease, and Treatment [Elektronische Daten] [Y. Bala, E. Seeman] Type 1 collagen matrix volume, its degree of completeness of its mineralization, the extent of collagen crosslinking and water content, and the non-collagenous proteins like osteopontin and osteocalcin comprise the main constituents of bone's material composition. Each influences material strength and change in different ways during advancing age, health, disease, and drug therapy. These traits are not quantifiable using bone densitometry and their plurality is better captured by the term bone ‘qualities' than ‘quality'. These qualities are the subject of this manuscript. Springer Science+Business Media New York, 2015 Bone water nationallicence Collagen nationallicence Mineralization nationallicence Osteopontin nationallicence Osteocalcin nationallicence Pentosidine nationallicence Qualities of bone nationallicence Bala Y. Laboratoire Vibrations Acoustique, Institut National des Sciences Appliquées de Lyon, Campus LyonTech la Doua, Villeurbanne, France aut Seeman E. Departments of Endocrinology and Medicine, Centaur Wing, Repatriation Campus, Austin Health, University of Melbourne, Waterdale rd, Heidelberg, 3081, Melbourne, Australia aut Calcified Tissue International Springer US; http://www.springer-ny.com 97/3(2015-09-01), 308-326 0171-967X 97:3<308 2015 97 223 https://doi.org/10.1007/s00223-015-9971-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00223-015-9971-y text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bala Y. Laboratoire Vibrations Acoustique, Institut National des Sciences Appliquées de Lyon, Campus LyonTech la Doua, Villeurbanne, France aut NATIONALLICENCE 700 1- Seeman E. Departments of Endocrinology and Medicine, Centaur Wing, Repatriation Campus, Austin Health, University of Melbourne, Waterdale rd, Heidelberg, 3081, Melbourne, Australia aut NATIONALLICENCE 773 0- Calcified Tissue International Springer US; http://www.springer-ny.com 97/3(2015-09-01), 308-326 0171-967X 97:3<308 2015 97 223