Fragility of Bone Material Controlled by Internal Interfaces
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 605520623 | ||
| 003 | CHVBK | ||
| 005 | 20210128100736.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20150901xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00223-015-9978-4 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00223-015-9978-4 | ||
| 245 | 0 | 0 | |a Fragility of Bone Material Controlled by Internal Interfaces |h [Elektronische Daten] |c [Wolfgang Wagermaier, Klaus Klaushofer, Peter Fratzl] |
| 520 | 3 | |a Bone material is built in a complex multiscale arrangement of mineralized collagen fibrils containing water, proteoglycans and some noncollagenous proteins. This organization is not static as bone is constantly remodeled and thus able to repair damaged tissue and adapt to the loading situation. In preventing fractures, the most important mechanical property is toughness, which is the ability to absorb impact energy without reaching complete failure. There is no simple explanation for the origin of the toughness of bone material, and this property depends in a complex way on the internal architecture of the material on all scales from nanometers to millimeters. Hence, fragility may have different mechanical origins, depending on which toughening mechanism is not working properly. This article reviews the toughening mechanisms described for bone material and attempts to put them in a clinical context, with the hope that future analysis of bone fragility may be guided by this collection of possible mechanistic origins. | |
| 540 | |a The Author(s), 2015 | ||
| 690 | 7 | |a Bone fragility |2 nationallicence | |
| 690 | 7 | |a Collagen |2 nationallicence | |
| 690 | 7 | |a Bone mineral |2 nationallicence | |
| 690 | 7 | |a Osteoporosis |2 nationallicence | |
| 690 | 7 | |a Bone material quality |2 nationallicence | |
| 700 | 1 | |a Wagermaier |D Wolfgang |u Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Research Campus Golm, 14424, Potsdam, Germany |4 aut | |
| 700 | 1 | |a Klaushofer |D Klaus |u First Medical Department, Hanusch Hospital, Ludwig Boltzmann Institute of Osteology at Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Heinrich Collin Str. 30, 1140, Vienna, Austria |4 aut | |
| 700 | 1 | |a Fratzl |D Peter |u Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Research Campus Golm, 14424, Potsdam, Germany |4 aut | |
| 773 | 0 | |t Calcified Tissue International |d Springer US; http://www.springer-ny.com |g 97/3(2015-09-01), 201-212 |x 0171-967X |q 97:3<201 |1 2015 |2 97 |o 223 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00223-015-9978-4 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a review-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00223-015-9978-4 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Wagermaier |D Wolfgang |u Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Research Campus Golm, 14424, Potsdam, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Klaushofer |D Klaus |u First Medical Department, Hanusch Hospital, Ludwig Boltzmann Institute of Osteology at Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Heinrich Collin Str. 30, 1140, Vienna, Austria |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fratzl |D Peter |u Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Research Campus Golm, 14424, Potsdam, Germany |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Calcified Tissue International |d Springer US; http://www.springer-ny.com |g 97/3(2015-09-01), 201-212 |x 0171-967X |q 97:3<201 |1 2015 |2 97 |o 223 | ||