The Mineral-Collagen Interface in Bone
| LEADER | caa a22 4500 | ||
|---|---|---|---|
| 001 | 605520666 | ||
| 003 | CHVBK | ||
| 005 | 20210128100736.0 | ||
| 007 | cr unu---uuuuu | ||
| 008 | 210128e20150901xx s 000 0 eng | ||
| 024 | 7 | 0 | |a 10.1007/s00223-015-9984-6 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s00223-015-9984-6 | ||
| 100 | 1 | |a Stock |D S. |u Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Ave., 60611-3008, Chicago, IL, USA |4 aut | |
| 245 | 1 | 4 | |a The Mineral-Collagen Interface in Bone |h [Elektronische Daten] |c [S. Stock] |
| 520 | 3 | |a The interface between collagen and the mineral reinforcement phase, carbonated hydroxyapatite (cAp), is essential for bone's remarkable functionality as a biological composite material. The very small dimensions of the cAp phase and the disparate natures of the reinforcement and matrix are essential to the material's performance but also complicate study of this interface. This article summarizes what is known about the cAp-collagen interface in bone and begins with descriptions of the matrix and reinforcement roles in composites, of the phases bounding the interface, of growth of cAp growing within the collagen matrix, and of the effect of intra- and extrafibrilar mineral on determinations of interfacial properties. Different observed interfacial interactions with cAp (collagen, water, non-collagenous proteins) are reviewed; experimental results on interface interactions during loading are reported as are their influence on macroscopic mechanical properties; conclusions of numerical modeling of interfacial interactions are also presented. The data suggest interfacial interlocking (bending of collagen molecules around cAp nanoplatelets) and water-mediated bonding between collagen and cAp are essential to load transfer. The review concludes with descriptions of areas where new research is needed to improve understanding of how the interface functions. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Bone |2 nationallicence | |
| 690 | 7 | |a Mineral-collagen interface |2 nationallicence | |
| 690 | 7 | |a Apatite |2 nationallicence | |
| 690 | 7 | |a Collagen |2 nationallicence | |
| 690 | 7 | |a Non-collagenous proteins |2 nationallicence | |
| 773 | 0 | |t Calcified Tissue International |d Springer US; http://www.springer-ny.com |g 97/3(2015-09-01), 262-280 |x 0171-967X |q 97:3<262 |1 2015 |2 97 |o 223 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s00223-015-9984-6 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s00223-015-9984-6 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 100 |E 1- |a Stock |D S. |u Department of Cell and Molecular Biology, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Ave., 60611-3008, Chicago, IL, USA |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Calcified Tissue International |d Springer US; http://www.springer-ny.com |g 97/3(2015-09-01), 262-280 |x 0171-967X |q 97:3<262 |1 2015 |2 97 |o 223 | ||