caa a22 4500 605520887 CHVBK 20210128100737.0 cr unu---uuuuu 210128e20151101xx s 000 0 eng 10.1007/s00223-015-0033-2 doi (NATIONALLICENCE)springer-10.1007/s00223-015-0033-2 Lee Kayoung Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, 633-165 Gaegum-dong, Busan Jin-Gu, 614-735, Busan, Korea aut Metabolic Syndrome and Osteoporosis in Relation to Muscle Mass [Elektronische Daten] [Kayoung Lee] This study aimed to examine the relationship between metabolic syndrome (MetS) and osteoporosis according to muscle mass levels and the joint relationship of MetS and muscle mass with osteoporosis in a representative population-based sample from the Korea National Health and Nutrition Examination Survey in 2010-2011. In 1654 men and 1979 women aged 50-93years, body composition and bone mineral density at the femur and lumbar spine were measured using dual-energy X-ray absorptiometry. Low- and high-muscle mass groups were identified using the mean sex-specific muscle mass of appendicular muscle mass/height2. The covariates were age, health behaviors, serum 25-OH vitamin D and parathyroid hormone, calcium intake, and hormone replacement therapy for women. Men and women with MetS (defined by the Adult Treatment Panel III) had 43 and 31% lower odds for osteoporosis, respectively, compared with their MetS-free counterparts after adjusting for muscle mass and covariates. When stratified by muscle mass, MetS was not associated with osteoporosis in men, while associated in women with higher muscle mass (OR 0.65, 95% CI 0.46-0.91). Compared with MetS-free men and women with lower muscle mass, the odds for osteoporosis were 45% and 23, 52 and 15%, and 72 and 46% lower among those with low muscle mass and MetS, high muscle mass without MetS, and high muscle mass and MetS, respectively (P for trend<0.001). Combination of high muscle mass and MetS was associated with lower prevalence of osteoporosis in Korean men and women. Springer Science+Business Media New York, 2015 Metabolic syndrome nationallicence Muscle mass nationallicence Osteoporosis nationallicence Bone mineral density nationallicence Calcified Tissue International Springer US; http://www.springer-ny.com 97/5(2015-11-01), 487-494 0171-967X 97:5<487 2015 97 223 https://doi.org/10.1007/s00223-015-0033-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00223-015-0033-2 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Lee Kayoung Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, 633-165 Gaegum-dong, Busan Jin-Gu, 614-735, Busan, Korea aut NATIONALLICENCE 773 0- Calcified Tissue International Springer US; http://www.springer-ny.com 97/5(2015-11-01), 487-494 0171-967X 97:5<487 2015 97 223