caa a22 4500 605521433 CHVBK 20210128100740.0 cr unu---uuuuu 210128e20150401xx s 000 0 eng 10.1007/s00223-015-9958-8 doi (NATIONALLICENCE)springer-10.1007/s00223-015-9958-8 Mays Simon Analysis and Investigation Division, English Heritage, Fort Cumberland, PO4 9LD, Portsmouth, UK aut Age-Associated Reduction in Cortical Bone in Males, Trends from the Third Century AD to the Present Day [Elektronische Daten] [Simon Mays] Osteoporosis is increasingly recognised as a health threat in the ageing male. Risk factors for osteoporosis appear to have increased through time. This study investigates the hypothesis that lifestyle changes (e.g. increasing sedentism, tobacco use) over the past 1,800years have resulted in greater age-related reduction in cortical bone in males in more recent compared with earlier times in England. Skeletons (N=215) from three English archaeological sites dating from the third to nineteenth century AD, together with comparison with a modern reference population, are used to investigate this hypothesis. Metacarpal cortical thickness is used as a measure of cortical bone status. Results of this cross-sectional study do not support the above hypothesis but instead suggest that patterns of age-related reduction in cortical bone in males have remained stable over an 1,800year period. Springer Science+Business Media New York, 2015 Osteoporosis nationallicence Epidemiology nationallicence Secular trend nationallicence Calcified Tissue International Springer US; http://www.springer-ny.com 96/4(2015-04-01), 370-371 0171-967X 96:4<370 2015 96 223 https://doi.org/10.1007/s00223-015-9958-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s00223-015-9958-8 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Mays Simon Analysis and Investigation Division, English Heritage, Fort Cumberland, PO4 9LD, Portsmouth, UK aut NATIONALLICENCE 773 0- Calcified Tissue International Springer US; http://www.springer-ny.com 96/4(2015-04-01), 370-371 0171-967X 96:4<370 2015 96 223