Ammonium chloride-catalyzed four-component sonochemical synthesis of novel hexahydroquinolines bearing a sulfonamide moiety

Verfasser / Beitragende:
[E. Hussein]
Ort, Verlag, Jahr:
2015
Enthalten in:
Russian Journal of Organic Chemistry, 51/1(2015-01-01), 54-64
Format:
Artikel (online)
ID: 605528454
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024 7 0 |a 10.1134/S1070428015010091  |2 doi 
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100 1 |a Hussein  |D E.  |u Department of Chemistry, Faculty of Science, Assiut University, 71516, Assiut, Egypt  |4 aut 
245 1 0 |a Ammonium chloride-catalyzed four-component sonochemical synthesis of novel hexahydroquinolines bearing a sulfonamide moiety  |h [Elektronische Daten]  |c [E. Hussein] 
520 3 |a Ammonium chloride as a very inexpensive and readily available reagent efficiently catalyzes one-pot four-component condensation of dimedone with aromatic aldehyde, malononitrile or ethyl cyanoacetate, and sulfonamide derivatives in ethanol at 70°C under ultrasonic irradiation to afford the corresponding 2-amino-4-aryl-1,4,5,6,7,8-hexahydroquinolines bearing a sulfonamide moiety in high yields. In comparison to conventional methods, high yields, easy work-up, and short reaction time are advantages of this sonochemical procedure. The effects of the catalyst, solvent, and temperature are assessed. 
540 |a Pleiades Publishing, Ltd., 2015 
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950 |B NATIONALLICENCE  |P 100  |E 1-  |a Hussein  |D E.  |u Department of Chemistry, Faculty of Science, Assiut University, 71516, Assiut, Egypt  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Russian Journal of Organic Chemistry  |d Pleiades Publishing  |g 51/1(2015-01-01), 54-64  |x 1070-4280  |q 51:1<54  |1 2015  |2 51  |o 11178