Asymmetric syntheses of the lactone core of tetrahydrolipstatin and tetrahydroesterastin and of the oriental hornet Vespa Orientalis pheromone

Verfasser / Beitragende:
[I. Mineeva]
Ort, Verlag, Jahr:
2015
Enthalten in:
Russian Journal of Organic Chemistry, 51/6(2015-06-01), 842-848
Format:
Artikel (online)
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024 7 0 |a 10.1134/S1070428015060044  |2 doi 
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100 1 |a Mineeva  |D I.  |u Belarusian State University, pr. Nezavisimosti 4, 220030, Minsk, Belarus  |4 aut 
245 1 0 |a Asymmetric syntheses of the lactone core of tetrahydrolipstatin and tetrahydroesterastin and of the oriental hornet Vespa Orientalis pheromone  |h [Elektronische Daten]  |c [I. Mineeva] 
520 3 |a A synthetic approach to the lactone core of the anti-obesity drugs tetrahydrolipstatin and tetrahydroesterastin has been developed starting from readily accessible methyl (5S)-5-{[tert-butyl(dimethyl)silyl]-oxy}-3-oxohexadecanoate. (6S)-6-Undecyltetrahydro-2H-pyran-2-one, the oriental hornet Vespa Orientalis pheromone, has also been synthesized. A formal synthesis of (3S,4R,6S)-dihydroxy-6-undecyltetrahydro-2H-pyran-2-one (metabolite of a fungus separated from mangrove seeds) has been proposed. 
540 |a Pleiades Publishing, Ltd., 2015 
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950 |B NATIONALLICENCE  |P 100  |E 1-  |a Mineeva  |D I.  |u Belarusian State University, pr. Nezavisimosti 4, 220030, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Russian Journal of Organic Chemistry  |d Pleiades Publishing  |g 51/6(2015-06-01), 842-848  |x 1070-4280  |q 51:6<842  |1 2015  |2 51  |o 11178