caa a22 4500 605528985 CHVBK 20210128100815.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1134/S1070428015090201 doi (NATIONALLICENCE)springer-10.1134/S1070428015090201 Development of synthetic approaches to macrocyclic glycoterpenoids on the basis of glucuronic acid and diterpenoid isosteviol [Elektronische Daten] [O. Andreeva, R. Sharipova, I. Strobykina, M. Kravchenko, A. Strobykina, A. Voloshina, R. Musin, V. Kataeva] An approach has been developed to the synthesis of macrocyclic glycoterpenoids containing diterpenoid isosteviol and glucuronic acid fragments. Selective screening revealed compounds exhibiting antitubercular activity against H37RV, M. Avium, and M. Terrae strains at a level comparable to the known antitubercular drugs isoniazid, ofloxacin, and pyrazinamide. The compound possessing the highest antitubercular activity is non-cytotoxic toward human erythrocytes. Pleiades Publishing, Ltd., 2015 Andreeva O. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut Sharipova R. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut Strobykina I. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut Kravchenko M. Ural Research Institute for Phthisiopulmonology, ul. 22-go Parts”ezda 50, 620039, Yekaterinburg, Russia aut Strobykina A. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut Voloshina A. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut Musin R. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut Kataeva V. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut Russian Journal of Organic Chemistry Pleiades Publishing 51/9(2015-09-01), 1324-1333 1070-4280 51:9<1324 2015 51 11178 https://doi.org/10.1134/S1070428015090201 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 review-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1134/S1070428015090201 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Andreeva O. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut NATIONALLICENCE 700 1- Sharipova R. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut NATIONALLICENCE 700 1- Strobykina I. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut NATIONALLICENCE 700 1- Kravchenko M. Ural Research Institute for Phthisiopulmonology, ul. 22-go Parts”ezda 50, 620039, Yekaterinburg, Russia aut NATIONALLICENCE 700 1- Strobykina A. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut NATIONALLICENCE 700 1- Voloshina A. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut NATIONALLICENCE 700 1- Musin R. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut NATIONALLICENCE 700 1- Kataeva V. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, ul. Arbuzova 8, Kazan, 420088, Tatarstan, Russia aut NATIONALLICENCE 773 0- Russian Journal of Organic Chemistry Pleiades Publishing 51/9(2015-09-01), 1324-1333 1070-4280 51:9<1324 2015 51 11178