Synthesis of ethyl (2 E ,5 S )-7-{[ tert -butyl(dimethyl)silyloxy]-methyl}-5-methylocta-2,7-dienoate, a universal C7-C14 building block for the preparation of amphidinolides B, D, G, H, and L

Verfasser / Beitragende:
[I. Mineeva]
Ort, Verlag, Jahr:
2015
Enthalten in:
Russian Journal of Organic Chemistry, 51/7(2015-07-01), 920-930
Format:
Artikel (online)
ID: 605529175
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024 7 0 |a 10.1134/S1070428015070052  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1134/S1070428015070052 
100 1 |a Mineeva  |D I.  |u Belarusian State University, pr. Nezavisimosti 4, 220030, Minsk, Belarus  |4 aut 
245 1 0 |a Synthesis of ethyl (2 E ,5 S )-7-{[ tert -butyl(dimethyl)silyloxy]-methyl}-5-methylocta-2,7-dienoate, a universal C7-C14 building block for the preparation of amphidinolides B, D, G, H, and L  |h [Elektronische Daten]  |c [I. Mineeva] 
520 3 |a A new simple and efficient procedure has been developed for the asymmetric synthesis of the C7-C14 building block for cytotoxic macrolactones, amphidinolides B, D, G, H, and L, on the basis of (4S,6S)-6-benzyloxymethyl-4-methyltetrahydro-2H-pyran-2-one prepared through cyclopropanol intermediates. 
540 |a Pleiades Publishing, Ltd., 2015 
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950 |B NATIONALLICENCE  |P 100  |E 1-  |a Mineeva  |D I.  |u Belarusian State University, pr. Nezavisimosti 4, 220030, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Russian Journal of Organic Chemistry  |d Pleiades Publishing  |g 51/7(2015-07-01), 920-930  |x 1070-4280  |q 51:7<920  |1 2015  |2 51  |o 11178