caa a22 4500 605529795 CHVBK 20210128100820.0 cr unu---uuuuu 210128e20151001xx s 000 0 eng 10.1134/S1070428015100152 doi (NATIONALLICENCE)springer-10.1134/S1070428015100152 Annulation of 6-aminouracils with 2,3-dimethoxy- and 2-fluorobenzaldehydes and 2-chloro-7-methoxyquinoline-3-carbaldehyde [Elektronische Daten] [R. Melik-Ohanjanyan, T. Hovsepyan, S. Israelyan, G. Karakhanyan, N. Minasyan] 6-R-Aminouracils reacted with 2,3-dimethoxybenzaldehyde to give 10-R-substituted 9-methoxy-5-deazaflavins. No expected 5-deazaflavins were obtained in analogous reactions of 2,3-dimethoxybenzaldehyde with 6-aminouracil hydrochlorides. On the other hand, the corresponding 5-deazaflavin and naphthyridine hydrochlorides were formed in the reactions of 6-aminouracil hydrochlorides with 2-fluorobenzaldehyde and 2-chloro-7-methoxyquinoline-3-carbaldehyde. The newly synthesized 9,10-substituted 5-deazaflavins and benzo[b]pyrimido[5,4-g][1,8]naphthyridines attract interest as potential biologically active substances and substrates for further structural modifications. Pleiades Publishing, Ltd., 2015 Melik-Ohanjanyan R. Mndzhoyan Institute of Fine Organic Chemistry Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut Hovsepyan T. Mndzhoyan Institute of Fine Organic Chemistry Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut Israelyan S. Mndzhoyan Institute of Fine Organic Chemistry Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut Karakhanyan G. Mndzhoyan Institute of Fine Organic Chemistry Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut Minasyan N. Molecular Structure Research Center Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut Russian Journal of Organic Chemistry Pleiades Publishing 51/10(2015-10-01), 1444-1448 1070-4280 51:10<1444 2015 51 11178 https://doi.org/10.1134/S1070428015100152 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1134/S1070428015100152 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Melik-Ohanjanyan R. Mndzhoyan Institute of Fine Organic Chemistry Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut NATIONALLICENCE 700 1- Hovsepyan T. Mndzhoyan Institute of Fine Organic Chemistry Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut NATIONALLICENCE 700 1- Israelyan S. Mndzhoyan Institute of Fine Organic Chemistry Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut NATIONALLICENCE 700 1- Karakhanyan G. Mndzhoyan Institute of Fine Organic Chemistry Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut NATIONALLICENCE 700 1- Minasyan N. Molecular Structure Research Center Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, pr. Azatutyan 26, 0014, Yerevan, Armenia aut NATIONALLICENCE 773 0- Russian Journal of Organic Chemistry Pleiades Publishing 51/10(2015-10-01), 1444-1448 1070-4280 51:10<1444 2015 51 11178