Synthesis of functional isoxazole derivatives proceeding from (5-arylisoxazol-3-yl)chloromethanes

Verfasser / Beitragende:
[V. Potkin, N. Bumagin, S. Petkevich, E. Dikusar, E. Semenova, P. Kurman, R. Zolotar', S. Pashkevich, T. Gurinovich, V. Kul'chitskii]
Ort, Verlag, Jahr:
2015
Enthalten in:
Russian Journal of Organic Chemistry, 51/8(2015-08-01), 1119-1130
Format:
Artikel (online)
ID: 605530335
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245 0 0 |a Synthesis of functional isoxazole derivatives proceeding from (5-arylisoxazol-3-yl)chloromethanes  |h [Elektronische Daten]  |c [V. Potkin, N. Bumagin, S. Petkevich, E. Dikusar, E. Semenova, P. Kurman, R. Zolotar', S. Pashkevich, T. Gurinovich, V. Kul'chitskii] 
520 3 |a Reaction of 3-chloromethyl-5-phenyl(p-tolyl)isoxazoles with substituted phenols under the conditions of Williamson reaction afforded the corresponding 3-aryloxymethyl-5-phenyl(p-tolyl)isoxazoles. Treating the latter with sodium methylate, sodium phenyl(benzyl, furfuryl)thiolates and morpholine in methanol resulted in the replacement of the chlorine atom in 3-chloromethyl-5-phenyl(p-tolyl)isoxazoles by methoxy-, phenyl-(benzyl, furfuryl)sulfanyl groups and morpholine residue. 
540 |a Pleiades Publishing, Ltd., 2015 
700 1 |a Potkin  |D V.  |u Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, 220072, Minsk, Belarus  |4 aut 
700 1 |a Bumagin  |D N.  |u Lomonosov Moscow State University, Moscow, Russia  |4 aut 
700 1 |a Petkevich  |D S.  |u Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, 220072, Minsk, Belarus  |4 aut 
700 1 |a Dikusar  |D E.  |u Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, 220072, Minsk, Belarus  |4 aut 
700 1 |a Semenova  |D E.  |u Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, 220072, Minsk, Belarus  |4 aut 
700 1 |a Kurman  |D P.  |u Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
700 1 |a Zolotar'  |D R.  |u Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
700 1 |a Pashkevich  |D S.  |u Physiology Institute, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
700 1 |a Gurinovich  |D T.  |u Physiology Institute, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
700 1 |a Kul'chitskii  |D V.  |u Physiology Institute, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
773 0 |t Russian Journal of Organic Chemistry  |d Pleiades Publishing  |g 51/8(2015-08-01), 1119-1130  |x 1070-4280  |q 51:8<1119  |1 2015  |2 51  |o 11178 
856 4 0 |u https://doi.org/10.1134/S1070428015080102  |q text/html  |z Onlinezugriff via DOI 
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900 7 |a Metadata rights reserved  |b Springer special CC-BY-NC licence  |2 nationallicence 
908 |D 1  |a research-article  |2 jats 
949 |B NATIONALLICENCE  |F NATIONALLICENCE  |b NL-springer 
950 |B NATIONALLICENCE  |P 856  |E 40  |u https://doi.org/10.1134/S1070428015080102  |q text/html  |z Onlinezugriff via DOI 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Potkin  |D V.  |u Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, 220072, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bumagin  |D N.  |u Lomonosov Moscow State University, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Petkevich  |D S.  |u Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, 220072, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Dikusar  |D E.  |u Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, 220072, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Semenova  |D E.  |u Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, ul. Surganova 13, 220072, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kurman  |D P.  |u Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zolotar'  |D R.  |u Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Pashkevich  |D S.  |u Physiology Institute, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Gurinovich  |D T.  |u Physiology Institute, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kul'chitskii  |D V.  |u Physiology Institute, National Academy of Sciences of Belarus, Minsk, Belarus  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Russian Journal of Organic Chemistry  |d Pleiades Publishing  |g 51/8(2015-08-01), 1119-1130  |x 1070-4280  |q 51:8<1119  |1 2015  |2 51  |o 11178