New approach to the synthesis of macrocyclic core of cytotoxic lactone (+)-neopeltolide. Synthesis of C7-C14 segment basing on cyclopropanol intermediates
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| 024 | 7 | 0 | |a 10.1134/S1070428015080023 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1134/S1070428015080023 | ||
| 100 | 1 | |a Mineeva |D I. |u Belorussian State University, pr. Nezavisimosti 4, 220030, Minsk, Belarus |4 aut | |
| 245 | 1 | 0 | |a New approach to the synthesis of macrocyclic core of cytotoxic lactone (+)-neopeltolide. Synthesis of C7-C14 segment basing on cyclopropanol intermediates |h [Elektronische Daten] |c [I. Mineeva] |
| 520 | 3 | |a A new retrosynthetic procedure was developed for the synthesis of the macrocyclic core of a cytotoxic lactone (+)-neopeltolide utilizing cyclopropanol intermediates. The synthesis was suggested and carried out of the C7-C16 segment of (+)-neopeltolide to obtain (4S,6S)-6-[(2S)-2-hydroxypentyl]-4-methyltetrahydro-2H-pyran-2-one. The possibility was demonstrated of a formal synthesis based on the obtained product of the potential antitumor pharmaceutical (+)-neopeltolide. | |
| 540 | |a Pleiades Publishing, Ltd., 2015 | ||
| 773 | 0 | |t Russian Journal of Organic Chemistry |d Pleiades Publishing |g 51/8(2015-08-01), 1061-1070 |x 1070-4280 |q 51:8<1061 |1 2015 |2 51 |o 11178 | |
| 856 | 4 | 0 | |u https://doi.org/10.1134/S1070428015080023 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1134/S1070428015080023 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 100 |E 1- |a Mineeva |D I. |u Belorussian State University, pr. Nezavisimosti 4, 220030, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Russian Journal of Organic Chemistry |d Pleiades Publishing |g 51/8(2015-08-01), 1061-1070 |x 1070-4280 |q 51:8<1061 |1 2015 |2 51 |o 11178 | ||