caa a22 4500 605530637 CHVBK 20210128100824.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1134/S1070428015050231 doi (NATIONALLICENCE)springer-10.1134/S1070428015050231 Synthesis of pyrrol-2-yl- and pyrazol-4-ylmethylidene derivatives of betulin and allobetulin [Elektronische Daten] [N. Babak, A. Semenenko, I. Gella, V. Musatov, S. Shishkina, N. Novikova, D. Sofronov, D. Morina, V. Lipson] Aldol-crotonic condensation of allobetulone and betulonic aldehyde with N-substituted pyrrole-2- and pyrazole-4-carbaldehydes afforded a series of new α,β-unsaturated ketones of lupane series. Their reduction provided 2-ylidene derivatives of allobetulin and betulin, potential chiral components of liquid crystal materials. Structures of 1-phenyl-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbaldehyde, (E)-2-{[3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}allobetulone, (E)-2-{[3-(4-bromophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-oxolup-20(29)-ene-28-carbaldehyde, (E)-2-{[3-(4-bromo-phenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}allobetulin, and (E)-2-{[3-(4-bromophe-nyl)-1-phenyl-1H-pyrazol-4-yl]-methylidene}lup-20(29)-ene-3,28-diol were established by X-ray diffraction (XRD) study. Pleiades Publishing, Ltd., 2015 Babak N. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut Semenenko A. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut Gella I. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut Musatov V. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut Shishkina S. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut Novikova N. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut Sofronov D. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut Morina D. Karazin Kharkiv National University, Kharkiv, Ukraine aut Lipson V. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut Russian Journal of Organic Chemistry Pleiades Publishing 51/5(2015-05-01), 715-726 1070-4280 51:5<715 2015 51 11178 https://doi.org/10.1134/S1070428015050231 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1134/S1070428015050231 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Babak N. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Semenenko A. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Gella I. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Musatov V. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Shishkina S. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Novikova N. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Sofronov D. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Morina D. Karazin Kharkiv National University, Kharkiv, Ukraine aut NATIONALLICENCE 700 1- Lipson V. Institute of Single Crystals, National Academy of Sciences of Ukraine, pr. Lenina 60, 61001, Kharkiv, Ukraine aut NATIONALLICENCE 773 0- Russian Journal of Organic Chemistry Pleiades Publishing 51/5(2015-05-01), 715-726 1070-4280 51:5<715 2015 51 11178