Modified Biginelli reaction in the synthesis of chromenopyrimidobenzimidazolones
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| 024 | 7 | 0 | |a 10.1134/S107042801505019X |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1134/S107042801505019X | ||
| 245 | 0 | 0 | |a Modified Biginelli reaction in the synthesis of chromenopyrimidobenzimidazolones |h [Elektronische Daten] |c [O. Mazhukina, A. Platonova, O. Fedotova, V. Vasin] |
| 520 | 3 | |a Biginelli reaction of 4-hydroxychromen-2-one with aromatic aldehydes and biazanucleophiles was investigated. The character of the substituent in the aromatic aldehyde and the reaction conditions affect its direction. The possibility to separate two probable regio isomers and the preparation of the chromenopyrimidobenzimidazolone with angular junction was demonstrated. The use of nuclear Overhauser effect (NOE 1D) made it possible to establish the spatial interaction between ortho-protons of chromene and benzimidazole fragments additionally confirming the structure of the obtained compound. The identification of the possible intermediates in the case of reacting 3-methyl-1H-pyrazol-5-amine as the azabinucleophile confirms the assumed scheme of 2H-chromen-2-ones formation under the applied conditions. | |
| 540 | |a Pleiades Publishing, Ltd., 2015 | ||
| 700 | 1 | |a Mazhukina |D O. |u Chemical Institute at Chernyshevskii Saratov State University, ul. Astrakhanskaya 83, 410012, Saratov, Russia |4 aut | |
| 700 | 1 | |a Platonova |D A. |u Chemical Institute at Chernyshevskii Saratov State University, ul. Astrakhanskaya 83, 410012, Saratov, Russia |4 aut | |
| 700 | 1 | |a Fedotova |D O. |u Chemical Institute at Chernyshevskii Saratov State University, ul. Astrakhanskaya 83, 410012, Saratov, Russia |4 aut | |
| 700 | 1 | |a Vasin |D V. |u Physical and Chemical Institute at Ogarev Mordovian State University, Saransk, Russia |4 aut | |
| 773 | 0 | |t Russian Journal of Organic Chemistry |d Pleiades Publishing |g 51/5(2015-05-01), 691-696 |x 1070-4280 |q 51:5<691 |1 2015 |2 51 |o 11178 | |
| 856 | 4 | 0 | |u https://doi.org/10.1134/S107042801505019X |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1134/S107042801505019X |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mazhukina |D O. |u Chemical Institute at Chernyshevskii Saratov State University, ul. Astrakhanskaya 83, 410012, Saratov, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Platonova |D A. |u Chemical Institute at Chernyshevskii Saratov State University, ul. Astrakhanskaya 83, 410012, Saratov, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Fedotova |D O. |u Chemical Institute at Chernyshevskii Saratov State University, ul. Astrakhanskaya 83, 410012, Saratov, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vasin |D V. |u Physical and Chemical Institute at Ogarev Mordovian State University, Saransk, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Russian Journal of Organic Chemistry |d Pleiades Publishing |g 51/5(2015-05-01), 691-696 |x 1070-4280 |q 51:5<691 |1 2015 |2 51 |o 11178 | ||