Correction of Hormonal and Metabolic Disorders in Male Rats with Developing Experimental Diabetes
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2879-8 |2 doi |
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| 245 | 0 | 0 | |a Correction of Hormonal and Metabolic Disorders in Male Rats with Developing Experimental Diabetes |h [Elektronische Daten] |c [N. Didebulidze, M. Kakabadze, N. Gordadze, I. Latsabidze, M. Kordzaya, I. Sikharulidze] |
| 520 | 3 | |a Synthetic radioinert androgen methyltrienolone administered daily for 2 weeks to male rats with severe diabetes led to a sharp increase in blood testosterone and was accompanied by reduction in glucose level due to an increase in tissue sensitivity to insulin. Normalization of plasma testosterone concentration contributed to saturation of active androgen receptors in the myocardium with testosterone; the number of free receptors decreased by 1.8 times. Testosterone that diminishes the catabolic effects of glucocorticoids improved the state of the myocardium, which was confirmed by activation of DNA and RNA synthesis. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a testosterone |2 nationallicence | |
| 690 | 7 | |a ischemia |2 nationallicence | |
| 690 | 7 | |a myocardium |2 nationallicence | |
| 690 | 7 | |a diabetes |2 nationallicence | |
| 700 | 1 | |a Didebulidze |D N. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | |
| 700 | 1 | |a Kakabadze |D M. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | |
| 700 | 1 | |a Gordadze |D N. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | |
| 700 | 1 | |a Latsabidze |D I. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | |
| 700 | 1 | |a Kordzaya |D M. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | |
| 700 | 1 | |a Sikharulidze |D I. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/1(2015-05-01), 20-23 |x 0007-4888 |q 159:1<20 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2879-8 |q text/html |z Onlinezugriff via DOI |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Didebulidze |D N. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kakabadze |D M. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gordadze |D N. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Latsabidze |D I. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kordzaya |D M. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sikharulidze |D I. |u I. A. Natishvili Institute of Experimental Morphology of I. Javakhishvili Tbilisi State University, Tbilisi, Georgia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/1(2015-05-01), 20-23 |x 0007-4888 |q 159:1<20 |1 2015 |2 159 |o 10517 | ||