caa a22 4500 605534861 CHVBK 20210128100844.0 cr unu---uuuuu 210128e20150501xx s 000 0 eng 10.1007/s10517-015-2899-4 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2899-4 Age-Related Features of Cardiomyocyte Ploidy in Patients with Hypertrophic Obstructive Cardiomyopathy [Elektronische Daten] [T. Sukhacheva, Yu. Chudinovskikh, M. Eremeeva, R. Serov] Endomyocardial biopsy samples of the interventricular septum from patients with hypertrophic cardiomyopathy isolated during myectomy were examined. We revealed significant variability of cardiomyocyte ploidy (from 2.9c to 13.5c) that directly correlated with myocyte size; the maximum ploidy was found in young patients. Ultrastructural signs of increased contractile and synthetic activity of cells were observed in patients with high DNA content in cardiomyocytes. Springer Science+Business Media New York, 2015 hypertrophic cardiomyopathy nationallicence age nationallicence cardiomyocyte ploidy nationallicence hypertrophy nationallicence ultrastructure nationallicence Sukhacheva T. A. N. Bakulev Research Centre for Cardiovascular Surgery, Russian Academy of Sciences, Moscow, Russia aut Chudinovskikh Yu A. N. Bakulev Research Centre for Cardiovascular Surgery, Russian Academy of Sciences, Moscow, Russia aut Eremeeva M. A. N. Bakulev Research Centre for Cardiovascular Surgery, Russian Academy of Sciences, Moscow, Russia aut Serov R. A. N. Bakulev Research Centre for Cardiovascular Surgery, Russian Academy of Sciences, Moscow, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/1(2015-05-01), 95-99 0007-4888 159:1<95 2015 159 10517 https://doi.org/10.1007/s10517-015-2899-4 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2899-4 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Sukhacheva T. A. N. Bakulev Research Centre for Cardiovascular Surgery, Russian Academy of Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Chudinovskikh Yu A. N. Bakulev Research Centre for Cardiovascular Surgery, Russian Academy of Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Eremeeva M. A. N. Bakulev Research Centre for Cardiovascular Surgery, Russian Academy of Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Serov R. A. N. Bakulev Research Centre for Cardiovascular Surgery, Russian Academy of Sciences, Moscow, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/1(2015-05-01), 95-99 0007-4888 159:1<95 2015 159 10517