Intraperitoneal Administration of Muramyl Dipeptide β-Heptylglycoside to Pregnant and Non-Pregnant Female Mice Modulates Production of Th1/Th2/Th17/Tr1 Cytokines by Splenocytes Ex Vivo
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2888-7 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2888-7 | ||
| 245 | 0 | 0 | |a Intraperitoneal Administration of Muramyl Dipeptide β-Heptylglycoside to Pregnant and Non-Pregnant Female Mice Modulates Production of Th1/Th2/Th17/Tr1 Cytokines by Splenocytes Ex Vivo |h [Elektronische Daten] |c [O. Kalyuzhin, K. Artem'eva, M. Boltovskaya, K. Bunyatyan, E. Inviyayeva, L. Vinnitskii, A. Karaulov] |
| 520 | 3 | |a Muramyl dipeptide β-heptylglycoside (C7MDP) was administered to non-pregnant CBA female mice and pregnant mice after non-abortion-prone mating (CBA×BALB/c) and mating associated with a high rate of spontaneous abortion (CBA×DBA/2). In non-pregnant females, C7MDP increased the production of IL-2, IL-4, IL-5, IL-6, IL-17, IFNγ, TNFα, and GM-CSF at constant production of IL-1α and IL-10. C7MDP increased the production of IL-10 and IL-17 and suppressed the production of IFNγ on day 8 of gestation in non-abortion-prone mouse couples and stimulated the synthesis of IL-4 and IFNγ, reduced IL-5 production, and slightly increased IL-1α secretion after abortion-prone mating. On day 14 of gestation, C7MDP elevated the yield of IL-2, IL-4, IFNγ, TNFα, and GM-CSF in CBA×BALB/c and CBA×DBA/2 couples and IL-17 in the fi rst variant of mating. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a muramyl dipeptide β-heptylglycoside |2 nationallicence | |
| 690 | 7 | |a mouse model of miscarriage |2 nationallicence | |
| 690 | 7 | |a Th1/Th2/ Th17/Tr1 cytokines |2 nationallicence | |
| 700 | 1 | |a Kalyuzhin |D O. |u Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University, Ministry of Health, Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Artem'eva |D K. |u Laboratory of Cell Biotechnology and Immunopathology, Research Institute of Human Morphology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Boltovskaya |D M. |u Laboratory of Cell Biotechnology and Immunopathology, Research Institute of Human Morphology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Bunyatyan |D K. |u Laboratory of Immunology and Regulatory Mechanisms in Surgery, B. V. Petrovskii Russian Research Center of Surgery, Moscow, Russia |4 aut | |
| 700 | 1 | |a Inviyayeva |D E. |u Laboratory of Immunology and Regulatory Mechanisms in Surgery, B. V. Petrovskii Russian Research Center of Surgery, Moscow, Russia |4 aut | |
| 700 | 1 | |a Vinnitskii |D L. |u Laboratory of Immunology and Regulatory Mechanisms in Surgery, B. V. Petrovskii Russian Research Center of Surgery, Moscow, Russia |4 aut | |
| 700 | 1 | |a Karaulov |D A. |u Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University, Ministry of Health, Russian Federation, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/1(2015-05-01), 53-57 |x 0007-4888 |q 159:1<53 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2888-7 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2888-7 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kalyuzhin |D O. |u Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University, Ministry of Health, Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Artem'eva |D K. |u Laboratory of Cell Biotechnology and Immunopathology, Research Institute of Human Morphology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Boltovskaya |D M. |u Laboratory of Cell Biotechnology and Immunopathology, Research Institute of Human Morphology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bunyatyan |D K. |u Laboratory of Immunology and Regulatory Mechanisms in Surgery, B. V. Petrovskii Russian Research Center of Surgery, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Inviyayeva |D E. |u Laboratory of Immunology and Regulatory Mechanisms in Surgery, B. V. Petrovskii Russian Research Center of Surgery, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vinnitskii |D L. |u Laboratory of Immunology and Regulatory Mechanisms in Surgery, B. V. Petrovskii Russian Research Center of Surgery, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Karaulov |D A. |u Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University, Ministry of Health, Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/1(2015-05-01), 53-57 |x 0007-4888 |q 159:1<53 |1 2015 |2 159 |o 10517 | ||