Antioxidant Defense System after Single and Chronic Administration of Obestatin and Its Fragment (1-4) to Normal and Overweight Male Rats
Gespeichert in:
Verfasser / Beitragende:
[E. Khirazova, A. Bayzhumanov, E. Motorykina, A. Devyatov, M. Maslova, A. Graf, N. Sokolova, M. Golubeva, A. Kamenskii]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/1(2015-05-01), 38-40
Format:
Artikel (online)
Online Zugang:
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2884-y |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2884-y | ||
| 245 | 0 | 0 | |a Antioxidant Defense System after Single and Chronic Administration of Obestatin and Its Fragment (1-4) to Normal and Overweight Male Rats |h [Elektronische Daten] |c [E. Khirazova, A. Bayzhumanov, E. Motorykina, A. Devyatov, M. Maslova, A. Graf, N. Sokolova, M. Golubeva, A. Kamenskii] |
| 520 | 3 | |a We studied the effects of anorectic peptide obestatin and its fragment (1-4) on the antioxidant defense system in animals with normal and experimentally induced increased body weight. In rats with normal body weight, no changes in activity of the antioxidant defense system 1 week after single administration of the substances. After chronic administration of obestatin and fragment (1-4) for 1 week, total antioxidant capacity of the plasma decreased; obestatin also lowered the content of TBA-reactive products. In the overweight rats, SOD-like activity in the plasma increased 1 week after chronic administration of obestatin. Hence, obestatin and its fragment (1-4) induced changes in the antioxidant defense system only after chronic administration. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a obestatin |2 nationallicence | |
| 690 | 7 | |a antioxidant defense system |2 nationallicence | |
| 690 | 7 | |a overweight |2 nationallicence | |
| 700 | 1 | |a Khirazova |D E. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Bayzhumanov |D A. |u Department of Biophysics, Biological Faculty, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Motorykina |D E. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Devyatov |D A. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Maslova |D M. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Graf |D A. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Sokolova |D N. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Golubeva |D M. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Kamenskii |D A. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/1(2015-05-01), 38-40 |x 0007-4888 |q 159:1<38 |1 2015 |2 159 |o 10517 | |
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| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2884-y |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Khirazova |D E. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bayzhumanov |D A. |u Department of Biophysics, Biological Faculty, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Motorykina |D E. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Devyatov |D A. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Maslova |D M. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Graf |D A. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sokolova |D N. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Golubeva |D M. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kamenskii |D A. |u Department of Human and Animal Physiology, M. V. Lomonosov State Moscow University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/1(2015-05-01), 38-40 |x 0007-4888 |q 159:1<38 |1 2015 |2 159 |o 10517 | ||