Morphology and Immunohistochemical Phenotype of the Thymus in Secondary Immunodeficiency
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3080-9 |2 doi |
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| 245 | 0 | 0 | |a Morphology and Immunohistochemical Phenotype of the Thymus in Secondary Immunodeficiency |h [Elektronische Daten] |c [G. Struchko, L. Merkulova, E. Moskvichev, O. Kostrova, M. Mikhailova, E. Drandrova] |
| 520 | 3 | |a The thymus of outbred male rats 5 months after splenectomy (experimental secondary immunodeficiency) was studied by common histological and immunohistochemical methods using monoclonal and polyclonal antibodies to CD3, CD30, CD68, synaptophysin, to S100, p53, bcl-2, and Ki-67 proteins. Removal of the spleen led to acute involution of the thymic parenchyma, which was replaced by the adipose tissue and was associated with restructuring of the thymopoietic and nonthymopoietic components of the gland, changes in cellular composition and antigenic phenotype of the lobular cortical and medullary matter, and by reduction of cell proliferation. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a thymus |2 nationallicence | |
| 690 | 7 | |a involution |2 nationallicence | |
| 690 | 7 | |a splenectomy |2 nationallicence | |
| 690 | 7 | |a immunodeficiency |2 nationallicence | |
| 700 | 1 | |a Struchko |D G. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | |
| 700 | 1 | |a Merkulova |D L. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | |
| 700 | 1 | |a Moskvichev |D E. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | |
| 700 | 1 | |a Kostrova |D O. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | |
| 700 | 1 | |a Mikhailova |D M. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | |
| 700 | 1 | |a Drandrova |D E. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/6(2015-10-01), 801-804 |x 0007-4888 |q 159:6<801 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3080-9 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3080-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Struchko |D G. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Merkulova |D L. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Moskvichev |D E. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kostrova |D O. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mikhailova |D M. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Drandrova |D E. |u Department of Normal and Topographic Anatomy with Operative Surgery, I. N. Ulyanov Chuvash State University, Cheboksary, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/6(2015-10-01), 801-804 |x 0007-4888 |q 159:6<801 |1 2015 |2 159 |o 10517 | ||