Effect of Afobazole and Betaine on DNA Damage in Placental and Embryonic Tissues of Rats with Experimental Streptozocin Diabetes
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3068-5 |2 doi |
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| 245 | 0 | 0 | |a Effect of Afobazole and Betaine on DNA Damage in Placental and Embryonic Tissues of Rats with Experimental Streptozocin Diabetes |h [Elektronische Daten] |c [V. Zabrodina, E. Shreder, O. Shreder, A. Durnev, S. Seredenin] |
| 520 | 3 | |a DNA comet assay showed that the level of DNA damage in the placental and embryonic tissues of rats with streptozotocin-induced diabetes mellitus increased on gestation days 14 and 20. Afobazole and betaine administered per os effectively decreased the level of genotoxic damage; afobazole was most efficient in doses of 10 and 50 mg/kg and betaine in a dose of 100 mg/kg. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a Streptozotocin |2 nationallicence | |
| 690 | 7 | |a diabetes |2 nationallicence | |
| 690 | 7 | |a afobazole |2 nationallicence | |
| 690 | 7 | |a betaine |2 nationallicence | |
| 690 | 7 | |a DNA comet assay |2 nationallicence | |
| 700 | 1 | |a Zabrodina |D V. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Shreder |D E. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Shreder |D O. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Durnev |D A. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Seredenin |D S. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/6(2015-10-01), 757-760 |x 0007-4888 |q 159:6<757 |1 2015 |2 159 |o 10517 | |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zabrodina |D V. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shreder |D E. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shreder |D O. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Durnev |D A. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Seredenin |D S. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/6(2015-10-01), 757-760 |x 0007-4888 |q 159:6<757 |1 2015 |2 159 |o 10517 | ||