Effects of Inhibitors of Necroptosis and Autophagy on Morphofunctional Characteristics of the Myocardium during Static Cold Storage of Donor Rat Heart
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3078-3 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-3078-3 | ||
| 245 | 0 | 0 | |a Effects of Inhibitors of Necroptosis and Autophagy on Morphofunctional Characteristics of the Myocardium during Static Cold Storage of Donor Rat Heart |h [Elektronische Daten] |c [Yu. Dmitriev, S. Minasyan, L. Vasina, E. Demchenko, M. Galagudza] |
| 520 | 3 | |a Cardioprotective effects of necrostatin-1 (necroptosis inhibitor) and 3-methyladenine (autophagy inhibitor) were studied on the model of long-term cold preservation of rat heart. Addition of necrostatin-1 (490 nmol/liter) or 3-methyladenine (4.5 mmol/liter) to custodiol preserving solution reduced myocardial infarction size and improved left-ventricular function during reperfusion after 8-h preservation at 4°C. Inhibition of necroptosis and autophagy contributed to the cardioprotective effect under conditions of cold preservation of the donor heart. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a necroptosis |2 nationallicence | |
| 690 | 7 | |a autophagy |2 nationallicence | |
| 690 | 7 | |a necrostatin-1 |2 nationallicence | |
| 690 | 7 | |a 3-methyladenine |2 nationallicence | |
| 690 | 7 | |a cold preservation |2 nationallicence | |
| 700 | 1 | |a Dmitriev |D Yu |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Minasyan |D S. |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Vasina |D L. |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Demchenko |D E. |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Galagudza |D M. |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/6(2015-10-01), 792-795 |x 0007-4888 |q 159:6<792 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3078-3 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3078-3 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Dmitriev |D Yu |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Minasyan |D S. |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vasina |D L. |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Demchenko |D E. |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Galagudza |D M. |u North-Western Federal Medical Research Center, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/6(2015-10-01), 792-795 |x 0007-4888 |q 159:6<792 |1 2015 |2 159 |o 10517 | ||