Effects of Geroprotectors on Age-Related Changes in Proteolytic Digestive Enzyme Activities at Different Lighting Conditions
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3069-4 |2 doi |
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| 245 | 0 | 0 | |a Effects of Geroprotectors on Age-Related Changes in Proteolytic Digestive Enzyme Activities at Different Lighting Conditions |h [Elektronische Daten] |c [A. Morozov, E. Khizhkin, E. Svechkina, I. Vinogradova, V. Ilyukha, V. Anisimov, V. Khavinson] |
| 520 | 3 | |a We studied the effect of melatonin and epithalon on age-related changes in proteolytic digestive enzyme activity in the pancreas and gastric mucosa of rats kept under different lighting conditions. In rats kept under standard illumination, pepsin activity and the total proteolytic activity in the stomach and pancreas increased by the age of 12 months, but then decreased. Constant and natural lighting disturbed the age dynamics of proteolytic digestive enzyme activity. Administration of melatonin and epithalon to animals exposed to constant lighting restored age dynamics of pepsin activity and little affected total proteolytic activity. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a proteolytic digestive enzymes |2 nationallicence | |
| 690 | 7 | |a melatonin |2 nationallicence | |
| 690 | 7 | |a epithalon |2 nationallicence | |
| 690 | 7 | |a illumination regimes |2 nationallicence | |
| 690 | 7 | |a aging |2 nationallicence | |
| 700 | 1 | |a Morozov |D A. |u Institute of Biology, Karelian Research Center, Russian Academy of Sciences, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Khizhkin |D E. |u Institute of Biology, Karelian Research Center, Russian Academy of Sciences, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Svechkina |D E. |u Institute of Biology, Karelian Research Center, Russian Academy of Sciences, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Vinogradova |D I. |u Petrozavodsk State University, Petrozavodsk, Republic of Karelia |4 aut | |
| 700 | 1 | |a Ilyukha |D V. |u Institute of Biology, Karelian Research Center, Russian Academy of Sciences, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Anisimov |D V. |u N. N. Petrov Research Institute of Oncology, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | |
| 700 | 1 | |a Khavinson |D V. |u St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/6(2015-10-01), 761-763 |x 0007-4888 |q 159:6<761 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3069-4 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3069-4 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Morozov |D A. |u Institute of Biology, Karelian Research Center, Russian Academy of Sciences, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Khizhkin |D E. |u Institute of Biology, Karelian Research Center, Russian Academy of Sciences, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Svechkina |D E. |u Institute of Biology, Karelian Research Center, Russian Academy of Sciences, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Vinogradova |D I. |u Petrozavodsk State University, Petrozavodsk, Republic of Karelia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ilyukha |D V. |u Institute of Biology, Karelian Research Center, Russian Academy of Sciences, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Anisimov |D V. |u N. N. Petrov Research Institute of Oncology, Ministry of Health of the Russian Federation, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Khavinson |D V. |u St. Petersburg Institute of Bioregulation and Gerontology, St. Petersburg, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/6(2015-10-01), 761-763 |x 0007-4888 |q 159:6<761 |1 2015 |2 159 |o 10517 | ||