Expression of HIF-1α in Multipotent Mesenchymal Stromal Cells under Hypoxic Conditions
Gespeichert in:
Verfasser / Beitragende:
[M. Pogodina, L. Buravkova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/3(2015-07-01), 355-357
Format:
Artikel (online)
Online Zugang:
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2961-2 |2 doi |
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| 245 | 0 | 0 | |a Expression of HIF-1α in Multipotent Mesenchymal Stromal Cells under Hypoxic Conditions |h [Elektronische Daten] |c [M. Pogodina, L. Buravkova] |
| 520 | 3 | |a According to the data of reverse-transcription-PCR, long-term culturing of multipotent mesenchymal stromal cells from human adipose tissue at 1% O2 (vs. standard 20% O2) led to a decrease in HIF-1α gene expression, while no changes in this parameter were revealed at 5% O2. Analysis of the time course of HIF-1α mRNA level showed that at the early terms of hypoxic exposure, the expression of this gene increased and the duration of this increase depended on the severity of hypoxia. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a multipotent mesenchymal stromal cells |2 nationallicence | |
| 690 | 7 | |a HIF-1α |2 nationallicence | |
| 690 | 7 | |a gene expression |2 nationallicence | |
| 690 | 7 | |a hypoxia |2 nationallicence | |
| 700 | 1 | |a Pogodina |D M. |u State Scientific Center Institute of Biomedical Problems, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Buravkova |D L. |u State Scientific Center Institute of Biomedical Problems, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/3(2015-07-01), 355-357 |x 0007-4888 |q 159:3<355 |1 2015 |2 159 |o 10517 | |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Pogodina |D M. |u State Scientific Center Institute of Biomedical Problems, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Buravkova |D L. |u State Scientific Center Institute of Biomedical Problems, Russian Academy of Medical Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/3(2015-07-01), 355-357 |x 0007-4888 |q 159:3<355 |1 2015 |2 159 |o 10517 | ||