Proliferative and Synthetic Activity of Nerve Cells after Combined or Individual Exposure to Hypoxia and Hypercapnia

Verfasser / Beitragende:
[P. Tregub, V. Kulikov, N. Rucheikin, E. Belova, Yu. Motin]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/3(2015-07-01), 334-336
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-2955-0  |2 doi 
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245 0 0 |a Proliferative and Synthetic Activity of Nerve Cells after Combined or Individual Exposure to Hypoxia and Hypercapnia  |h [Elektronische Daten]  |c [P. Tregub, V. Kulikov, N. Rucheikin, E. Belova, Yu. Motin] 
520 3 |a We compared synthetic and proliferative activity of brain cells in rats exposed hypoxia, hypercapnia, or both prior to experimental focal stroke. The mean number of nucleolus organizer regions in penumbra neurons did not change after normobaric hypoxia, but increased after permissive hypercapnia or hypercapnic hypoxia. These data attest to activation of proliferative and synthetic functions in nerve cells, which plays an important role in the neuroprotective mechanisms under conditions of combined exposure to hypoxia and hypercapnia. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a hypoxia  |2 nationallicence 
690 7 |a hypercapnia  |2 nationallicence 
690 7 |a stroke  |2 nationallicence 
690 7 |a brain  |2 nationallicence 
690 7 |a nucleolus organizer region  |2 nationallicence 
700 1 |a Tregub  |D P.  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
700 1 |a Kulikov  |D V.  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
700 1 |a Rucheikin  |D N.  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
700 1 |a Belova  |D E.  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
700 1 |a Motin  |D Yu  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Tregub  |D P.  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kulikov  |D V.  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Rucheikin  |D N.  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Belova  |D E.  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Motin  |D Yu  |u Ministry of Health of the Russian Federation, Altai State Medical University, Barnaul, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/3(2015-07-01), 334-336  |x 0007-4888  |q 159:3<334  |1 2015  |2 159  |o 10517