Neuroprotective and Antioxidant Effects of Neuroglutam in Cerebral Ischemia
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2964-z |2 doi |
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| 245 | 0 | 0 | |a Neuroprotective and Antioxidant Effects of Neuroglutam in Cerebral Ischemia |h [Elektronische Daten] |c [I. Tyurenkov, E. Volotova, D. Kurkin, N. Mazina, D. Bakulin, I. Logvinov, T. Antipova] |
| 520 | 3 | |a We studied in vitro and in vivo neuroprotective and antioxidant properties of neuroglutam, a new glutamic acid derivative. In experiments on immortalized mouse hippocampal cell line HT22, neuroglutam exhibited a neuroprotective effect in the model of oxidative stress after its introduction, both before and after H2O2. In vivo study on animals treated with neuroglutam against the background of cerebral ischemia modeled by irreversible occlusion of the common carotid arteries showed that plasma level of TBA-active products was signifi cantly lower and activities of cell antioxidant enzymes (superoxide dismutase and catalase) were higher than in control animals receiving saline under the same conditions. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a neuroprotective properties |2 nationallicence | |
| 690 | 7 | |a antioxidant system |2 nationallicence | |
| 690 | 7 | |a neuroglutam |2 nationallicence | |
| 700 | 1 | |a Tyurenkov |D I. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Volotova |D E. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Kurkin |D D. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Mazina |D N. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Bakulin |D D. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Logvinov |D I. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Antipova |D T. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/3(2015-07-01), 365-367 |x 0007-4888 |q 159:3<365 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2964-z |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2964-z |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tyurenkov |D I. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Volotova |D E. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kurkin |D D. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mazina |D N. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bakulin |D D. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Logvinov |D I. |u Volgograd State Medical University, Russian Ministry of Health, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Antipova |D T. |u V. V. Zakusov Research Institute of Pharmacology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/3(2015-07-01), 365-367 |x 0007-4888 |q 159:3<365 |1 2015 |2 159 |o 10517 | ||