Effect of Antioxidant Echinochrome A on Bleomycin-Induced Pulmonary Fibrosis

Verfasser / Beitragende:
[O. Lebed'ko, B. Ryzhavskii, O. Demidova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/3(2015-07-01), 351-354
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-2960-3  |2 doi 
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245 0 0 |a Effect of Antioxidant Echinochrome A on Bleomycin-Induced Pulmonary Fibrosis  |h [Elektronische Daten]  |c [O. Lebed'ko, B. Ryzhavskii, O. Demidova] 
520 3 |a We studied the protective effect of antioxidant echinochrome A on bleomycin-induced pulmonary fi brosis in rats at the early stages of postnatal ontogeny. Administration of echinochrome A was shown to reduce the severity of bleomycin-induced oxidative stress in the lungs, prevented the development of hypertrophy of interalveolar connective tissue and peribronchial lymphoid infi ltration, and normalized the ratio of volume densities of interalveolar septa and alveolar lumen. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a bleomycin  |2 nationallicence 
690 7 |a pulmonary fi brosis  |2 nationallicence 
690 7 |a antioxidant  |2 nationallicence 
690 7 |a echinochrome A  |2 nationallicence 
700 1 |a Lebed'ko  |D O.  |u Khabarovsk Division of the Far-Eastern Scientific Center for Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Science - Research Institute of Maternal and Child Welfare, Khabarovsk, Russia  |4 aut 
700 1 |a Ryzhavskii  |D B.  |u Department of Histology, Far-Eastern State Medical University, Khabarovsk, Russia  |4 aut 
700 1 |a Demidova  |D O.  |u Department of Histology, Far-Eastern State Medical University, Khabarovsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/3(2015-07-01), 351-354  |x 0007-4888  |q 159:3<351  |1 2015  |2 159  |o 10517 
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908 |D 1  |a research-article  |2 jats 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Lebed'ko  |D O.  |u Khabarovsk Division of the Far-Eastern Scientific Center for Physiology and Pathology of Respiration, Siberian Division of the Russian Academy of Medical Science - Research Institute of Maternal and Child Welfare, Khabarovsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Ryzhavskii  |D B.  |u Department of Histology, Far-Eastern State Medical University, Khabarovsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Demidova  |D O.  |u Department of Histology, Far-Eastern State Medical University, Khabarovsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/3(2015-07-01), 351-354  |x 0007-4888  |q 159:3<351  |1 2015  |2 159  |o 10517