Differences in Active Avoidance Conditioning in Male and Female Rats with Experimental Anxiety-Depressive Disorder
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2956-z |2 doi |
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| 245 | 0 | 0 | |a Differences in Active Avoidance Conditioning in Male and Female Rats with Experimental Anxiety-Depressive Disorder |h [Elektronische Daten] |c [N. Khlebnikova, N. Krupina, E. Kushnareva, I. Orlova] |
| 520 | 3 | |a Using rat model of experimental anxiety-depressive disorder caused by postnatal administration of methionyl-2(S)-cyanopyrrolidine, an inhibitor of dipeptidyl peptidase IV, we compared conditioned active avoidance response and memory retention in males and females. In experimental males and females, conditioning was impaired in comparison with the control. In experimental groups, females were worse learners than males, while in control groups, females were better learners than males. Memory retention in experimental animals did not differ from that in controls 24 h after learning. Two months after learning, control females demonstrated better retention than control males. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a model |2 nationallicence | |
| 690 | 7 | |a anxiety-depressive disorder |2 nationallicence | |
| 690 | 7 | |a conditioned active avoidance response |2 nationallicence | |
| 690 | 7 | |a rat |2 nationallicence | |
| 700 | 1 | |a Khlebnikova |D N. |u Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Krupina |D N. |u Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Kushnareva |D E. |u Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Moscow, Russia |4 aut | |
| 700 | 1 | |a Orlova |D I. |u Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/3(2015-07-01), 337-340 |x 0007-4888 |q 159:3<337 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2956-z |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2956-z |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Khlebnikova |D N. |u Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Krupina |D N. |u Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kushnareva |D E. |u Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Orlova |D I. |u Laboratory of General Pathology of the Nervous System, Research Institute of General Pathology and Pathophysiology, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/3(2015-07-01), 337-340 |x 0007-4888 |q 159:3<337 |1 2015 |2 159 |o 10517 | ||