Changes in the Morphological and Immunological Characteristics of Mel Ibr Melanoma Cells in Response to Chicken Embryo Extract

Verfasser / Beitragende:
[N. Suraeva, L. Morozova, A. Samoilov, O. Burova, V. Golubeva, M. Baryshnikova, A. Baryshnikov]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/4(2015-08-01), 520-523
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-3007-5  |2 doi 
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245 0 0 |a Changes in the Morphological and Immunological Characteristics of Mel Ibr Melanoma Cells in Response to Chicken Embryo Extract  |h [Elektronische Daten]  |c [N. Suraeva, L. Morozova, A. Samoilov, O. Burova, V. Golubeva, M. Baryshnikova, A. Baryshnikov] 
520 3 |a Exposure of Mel Ibr human melanoma cells to chicken embryo extract resulted in the appearance of a subclone with morphological and growth characteristics similar to those of embryonic stem cells. The subclone differed from the parental line cells by a sharply reduced percentage of HLA-DR+ and CD54+ cells, a significantly elevated percentage of CD63+ cells, and appearance of CD133+ and Oct-4A+ cells. Hence, the subclone cells were characterized by the same features as stem tumor cells and could be responsible for further progress of tumor growth. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a chicken embryo extract  |2 nationallicence 
690 7 |a melanoma cell line  |2 nationallicence 
690 7 |a dedifferentiation  |2 nationallicence 
690 7 |a subclone  |2 nationallicence 
700 1 |a Suraeva  |D N.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Morozova  |D L.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Samoilov  |D A.  |u All-Russian Research Institute of Preservation Technology, Vidnoe, Moscow Region, Russia  |4 aut 
700 1 |a Burova  |D O.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Golubeva  |D V.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Baryshnikova  |D M.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
700 1 |a Baryshnikov  |D A.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/4(2015-08-01), 520-523  |x 0007-4888  |q 159:4<520  |1 2015  |2 159  |o 10517 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Suraeva  |D N.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Morozova  |D L.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Samoilov  |D A.  |u All-Russian Research Institute of Preservation Technology, Vidnoe, Moscow Region, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Burova  |D O.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Golubeva  |D V.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Baryshnikova  |D M.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Baryshnikov  |D A.  |u N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/4(2015-08-01), 520-523  |x 0007-4888  |q 159:4<520  |1 2015  |2 159  |o 10517