caa a22 4500 605535728 CHVBK 20210128100849.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s10517-015-3007-5 doi (NATIONALLICENCE)springer-10.1007/s10517-015-3007-5 Changes in the Morphological and Immunological Characteristics of Mel Ibr Melanoma Cells in Response to Chicken Embryo Extract [Elektronische Daten] [N. Suraeva, L. Morozova, A. Samoilov, O. Burova, V. Golubeva, M. Baryshnikova, A. Baryshnikov] Exposure of Mel Ibr human melanoma cells to chicken embryo extract resulted in the appearance of a subclone with morphological and growth characteristics similar to those of embryonic stem cells. The subclone differed from the parental line cells by a sharply reduced percentage of HLA-DR+ and CD54+ cells, a significantly elevated percentage of CD63+ cells, and appearance of CD133+ and Oct-4A+ cells. Hence, the subclone cells were characterized by the same features as stem tumor cells and could be responsible for further progress of tumor growth. Springer Science+Business Media New York, 2015 chicken embryo extract nationallicence melanoma cell line nationallicence dedifferentiation nationallicence subclone nationallicence Suraeva N. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut Morozova L. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut Samoilov A. All-Russian Research Institute of Preservation Technology, Vidnoe, Moscow Region, Russia aut Burova O. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut Golubeva V. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut Baryshnikova M. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut Baryshnikov A. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/4(2015-08-01), 520-523 0007-4888 159:4<520 2015 159 10517 https://doi.org/10.1007/s10517-015-3007-5 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3007-5 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Suraeva N. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Morozova L. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Samoilov A. All-Russian Research Institute of Preservation Technology, Vidnoe, Moscow Region, Russia aut NATIONALLICENCE 700 1- Burova O. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Golubeva V. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Baryshnikova M. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut NATIONALLICENCE 700 1- Baryshnikov A. N. N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/4(2015-08-01), 520-523 0007-4888 159:4<520 2015 159 10517