Effect of hrWnt7a on Human Retinal Pigment Epithelial Cells In Vitro
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3010-x |2 doi |
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| 245 | 0 | 0 | |a Effect of hrWnt7a on Human Retinal Pigment Epithelial Cells In Vitro |h [Elektronische Daten] |c [A. Kuznetsova, A. Kurinov, E. Chentsova, P. Makarov, M. Aleksandrova] |
| 520 | 3 | |a Human recombinant protein Wnt7a (hrWnt7a) inhibits cell proliferative activity and triggers cell polarization. Although cell polarization process was maintained only over a short time, probably via microenvironmental stimuli, hrWnt7a is involved in the transformation of the retinal pigment epithelium. Analysis of Wnt signaling pathway and its regulation will help to understand the processes in retinal pigment epithelial cells under pathological conditions, which can be useful in developing new generation drugs. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a human retinal pigment epithelium |2 nationallicence | |
| 690 | 7 | |a cell culture |2 nationallicence | |
| 690 | 7 | |a recombinant human protein Wnt7a |2 nationallicence | |
| 690 | 7 | |a MTT test |2 nationallicence | |
| 690 | 7 | |a immunohistochemistry |2 nationallicence | |
| 700 | 1 | |a Kuznetsova |D A. |u N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Kurinov |D A. |u N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia |4 aut | |
| 700 | 1 | |a Chentsova |D E. |u Helmholtz Moscow Research Institute of Eye Diseases, Moscow, Russia |4 aut | |
| 700 | 1 | |a Makarov |D P. |u Helmholtz Moscow Research Institute of Eye Diseases, Moscow, Russia |4 aut | |
| 700 | 1 | |a Aleksandrova |D M. |u N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/4(2015-08-01), 534-540 |x 0007-4888 |q 159:4<534 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3010-x |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3010-x |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuznetsova |D A. |u N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kurinov |D A. |u N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Chentsova |D E. |u Helmholtz Moscow Research Institute of Eye Diseases, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Makarov |D P. |u Helmholtz Moscow Research Institute of Eye Diseases, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Aleksandrova |D M. |u N. K. Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/4(2015-08-01), 534-540 |x 0007-4888 |q 159:4<534 |1 2015 |2 159 |o 10517 | ||