caa a22 4500 605535817 CHVBK 20210128100849.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s10517-015-2994-6 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2994-6 Characteristics of Circulating Immune Complexes in HIV-Infected Patients with Different Viral Load [Elektronische Daten] [L. Korolevskaya, K. Shmagel, N. Shmagel] Serum concentration of antiviral antibodies was measured in HIV-infected patients with different viral load. It was found that higher concentrations of HIV-antigens correspond to higher titer of antiviral antibodies. Circulating immune complexes were isolated from patients' serum to estimate their size and immunoglobulin composition. High levels of small IgG- and IgM-containing complexes were identified in HIV-infected patients. In patients receiving antiretroviral treatment, the content of these complexes was significantly lower than in patients with high HIV load. This attests to positive role of specific therapy in preventing immune complex-associated pathology in HIV patients. Springer Science+Business Media New York, 2015 HIV-infection nationallicence circulating immune complexes nationallicence viral load nationallicence antiretroviral treatment nationallicence Korolevskaya L. Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia aut Shmagel K. Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia aut Shmagel N. Regional Center on Prophylaxis and Combating of AIDS and Infection Diseases, Perm', Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/4(2015-08-01), 469-471 0007-4888 159:4<469 2015 159 10517 https://doi.org/10.1007/s10517-015-2994-6 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2994-6 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Korolevskaya L. Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia aut NATIONALLICENCE 700 1- Shmagel K. Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Ekaterinburg, Russia aut NATIONALLICENCE 700 1- Shmagel N. Regional Center on Prophylaxis and Combating of AIDS and Infection Diseases, Perm', Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/4(2015-08-01), 469-471 0007-4888 159:4<469 2015 159 10517