Suppression of ITGB4 Gene Expression in PC-3 Cells with Short Interfering RNA Induces Changes in the Expression of β-Integrins Associated with RGD-Receptors
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3011-9 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-3011-9 | ||
| 245 | 0 | 0 | |a Suppression of ITGB4 Gene Expression in PC-3 Cells with Short Interfering RNA Induces Changes in the Expression of β-Integrins Associated with RGD-Receptors |h [Elektronische Daten] |c [E. Knyazev, K. Nyushko, B. Alekseev, T. Samatov, M. Shkurnikov] |
| 520 | 3 | |a We studied the effect of transfection of PC-3 prostate cancer cells with a plasmid encoding shRNA complimentary to a fragment of integrin β4 (ITGB4). The results attest to considerable changes in the transcriptome of transfected cells. For instance, compensatory changes in the expression of integrin family genes were found. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a integrin |2 nationallicence | |
| 690 | 7 | |a RNA interference |2 nationallicence | |
| 690 | 7 | |a ITGB4 |2 nationallicence | |
| 690 | 7 | |a prostate cancer |2 nationallicence | |
| 690 | 7 | |a metastasizing |2 nationallicence | |
| 700 | 1 | |a Knyazev |D E. |u BioClinicum Research and Technical Centre, Moscow, Russia |4 aut | |
| 700 | 1 | |a Nyushko |D K. |u Federal Medical Research Center, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Alekseev |D B. |u Federal Medical Research Center, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | |
| 700 | 1 | |a Samatov |D T. |u BioClinicum Research and Technical Centre, Moscow, Russia |4 aut | |
| 700 | 1 | |a Shkurnikov |D M. |u BioClinicum Research and Technical Centre, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/4(2015-08-01), 541-545 |x 0007-4888 |q 159:4<541 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3011-9 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3011-9 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Knyazev |D E. |u BioClinicum Research and Technical Centre, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Nyushko |D K. |u Federal Medical Research Center, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Alekseev |D B. |u Federal Medical Research Center, Ministry of Health of the Russian Federation, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Samatov |D T. |u BioClinicum Research and Technical Centre, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Shkurnikov |D M. |u BioClinicum Research and Technical Centre, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/4(2015-08-01), 541-545 |x 0007-4888 |q 159:4<541 |1 2015 |2 159 |o 10517 | ||