caa a22 4500 60553585X CHVBK 20210128105200.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s10517-015-2997-3 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2997-3 Role of JNK and Contribution of p53 to the Realization of the Growth Potential of Mesenchymal Precursor Cells under the Effect of Fibroblast Growth Factor [Elektronische Daten] [G. Zyuz'kov, V. Zhdanov, E. Udut, L. Miroshnichenko, T. Khrichkova, M. Danilets, E. Simanina, A. Chaikovskii, V. Agafonov, E. Sherstoboev, M. Minakova, Ya. Burmina, V. Udut, A. Dygai] The role of JNK-mediated signal pathway and participation of p53 transcription factor in stimulation of mesenchymal precursor cell function by the fibroblast growth factor was studied. The levels of fibroblast colony- and cluster formation and proliferative activity of mesenchymal precursors increased in response to JNK and p53 specific inhibitors. JNK and p53 blockers did not change the rate of fibroblast growth factor-induced progenitor element differentiation. Springer Science+Business Media New York, 2015 JNK nationallicence p53 nationallicence fibroblast growth factor nationallicence progenitor cells nationallicence regenerative medicine nationallicence Zyuz'kov G. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Zhdanov V. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Udut E. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Miroshnichenko L. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Khrichkova T. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Danilets M. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Simanina E. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Chaikovskii A. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Agafonov V. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Sherstoboev E. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Minakova M. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Burmina Ya E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Udut V. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Dygai A. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/4(2015-08-01), 479-481 0007-4888 159:4<479 2015 159 10517 https://doi.org/10.1007/s10517-015-2997-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2997-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zyuz'kov G. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Zhdanov V. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Udut E. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Miroshnichenko L. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Khrichkova T. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Danilets M. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Simanina E. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Chaikovskii A. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Agafonov V. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Sherstoboev E. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Minakova M. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Burmina Ya E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Udut V. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Dygai A. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/4(2015-08-01), 479-481 0007-4888 159:4<479 2015 159 10517 SWISSBIB 60553585X