caa a22 4500 605535906 CHVBK 20210128100850.0 cr unu---uuuuu 210128e20150801xx s 000 0 eng 10.1007/s10517-015-2981-y doi (NATIONALLICENCE)springer-10.1007/s10517-015-2981-y Dzgoev S. K. L. Khetagurov North Ossetian State University; Vladikavkaz Research Center of the Russian Academy of Sciences and the Government of the Republic of North Ossetia-Alania, Vladikavkaz, Russia aut Selective V2-Agonist of Vasopressin Desmopressin Stimulates Activity of Serum Hyaluronidase [Elektronische Daten] [S. Dzgoev] Effects of desmopressin (arginine vasopressin V2 receptor agonist) were studied for elucidation of the possible role of the kidneys in the regulation of blood hyaluronidase activity. Similar to vasopressin, intraperitoneal administration of desmopressin to Wistar rats increased blood hyaluronidase activity by 30%. Against the background of water load, nether desmopressin nor vasopressin increased blood hyaluronidase activity. The possibility of renal secretion of hyaluronidase into the blood as a mechanism of antidiuretic activity of vasopressin and its role in the regulation of water metabolism are discussed. Springer Science+Business Media New York, 2015 hyaluronic acid nationallicence hyaluronidase nationallicence desmopressin nationallicence vasopressin nationallicence blood plasma nationallicence Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/4(2015-08-01), 424-426 0007-4888 159:4<424 2015 159 10517 https://doi.org/10.1007/s10517-015-2981-y text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2981-y text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Dzgoev S. K. L. Khetagurov North Ossetian State University; Vladikavkaz Research Center of the Russian Academy of Sciences and the Government of the Republic of North Ossetia-Alania, Vladikavkaz, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/4(2015-08-01), 424-426 0007-4888 159:4<424 2015 159 10517