The Use of Autologous Mesenchymal Stem Cells for Cell Therapy of Patients with Amyotrophic Lateral Sclerosis in Belarus
Gespeichert in:
Verfasser / Beitragende:
[Yu. Rushkevich, S. Kosmacheva, G. Zabrodets, S. Ignatenko, N. Goncharova, I. Severin, S. Likhachev, M. Potapnev]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/4(2015-08-01), 576-581
Format:
Artikel (online)
Online Zugang:
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3017-3 |2 doi |
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| 245 | 0 | 4 | |a The Use of Autologous Mesenchymal Stem Cells for Cell Therapy of Patients with Amyotrophic Lateral Sclerosis in Belarus |h [Elektronische Daten] |c [Yu. Rushkevich, S. Kosmacheva, G. Zabrodets, S. Ignatenko, N. Goncharova, I. Severin, S. Likhachev, M. Potapnev] |
| 520 | 3 | |a We studied a new method of treatment of amyotrophic lateral sclerosis with autologous mesenchymal stem cells. Autologous mesenchymal stem cells were injected intravenously (intact cells) or via lumbar puncture (cells committed to neuronal differentiation). Evaluation of the results of cell therapy after 12-month follow-up revealed slowing down of the disease progression in 10 patients in comparison with the control group consisting of 15 patients. The cell therapy was safe for the patients. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a amyotrophic lateral sclerosis |2 nationallicence | |
| 690 | 7 | |a autologous mesenchymal stem cells |2 nationallicence | |
| 690 | 7 | |a neurogenic differentiation |2 nationallicence | |
| 690 | 7 | |a ALSFRS-R |2 nationallicence | |
| 690 | 7 | |a Karnofsky scale |2 nationallicence | |
| 700 | 1 | |a Rushkevich |D Yu |u Republican Research-and-Practical Center of Neurology and Neurosurgery, Minsk, Belarus |4 aut | |
| 700 | 1 | |a Kosmacheva |D S. |u Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus |4 aut | |
| 700 | 1 | |a Zabrodets |D G. |u Republican Research-and-Practical Center of Neurology and Neurosurgery, Minsk, Belarus |4 aut | |
| 700 | 1 | |a Ignatenko |D S. |u Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus |4 aut | |
| 700 | 1 | |a Goncharova |D N. |u Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus |4 aut | |
| 700 | 1 | |a Severin |D I. |u Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus |4 aut | |
| 700 | 1 | |a Likhachev |D S. |u Republican Research-and-Practical Center of Neurology and Neurosurgery, Minsk, Belarus |4 aut | |
| 700 | 1 | |a Potapnev |D M. |u Belorussian State Medical University, Minsk, Belarus |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/4(2015-08-01), 576-581 |x 0007-4888 |q 159:4<576 |1 2015 |2 159 |o 10517 | |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Rushkevich |D Yu |u Republican Research-and-Practical Center of Neurology and Neurosurgery, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kosmacheva |D S. |u Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zabrodets |D G. |u Republican Research-and-Practical Center of Neurology and Neurosurgery, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ignatenko |D S. |u Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Goncharova |D N. |u Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Severin |D I. |u Republican Research-and-Practical Center of Transfusion and Medical Biotechnologies, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Likhachev |D S. |u Republican Research-and-Practical Center of Neurology and Neurosurgery, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Potapnev |D M. |u Belorussian State Medical University, Minsk, Belarus |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/4(2015-08-01), 576-581 |x 0007-4888 |q 159:4<576 |1 2015 |2 159 |o 10517 | ||