Characteristics of Mononuclear Extracellular Traps in the Offspring of Female Rats with Drug-Induced Hepatitis

Verfasser / Beitragende:
[G. Bryukhin, A. Shopova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/4(2015-08-01), 435-437
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-2984-8  |2 doi 
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245 0 0 |a Characteristics of Mononuclear Extracellular Traps in the Offspring of Female Rats with Drug-Induced Hepatitis  |h [Elektronische Daten]  |c [G. Bryukhin, A. Shopova] 
520 3 |a We studied the effect of experimental tetracycline-induced liver injury in mothers on the capacity of macrophages from various compartments to form traps and on activity of extracellular macrophage traps in the offspring. Trap-forming capacity was evaluated by the number of traps. We found reduction in the number and suppression of activity of the macrophage extracellular traps in the offspring of females with experimental liver injury. The findings suggest that mothers with drug-induced liver injury produce physiologically immature offspring with reduced unspecific resistance. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a extracellular traps  |2 nationallicence 
690 7 |a activity of macrophagal traps  |2 nationallicence 
690 7 |a killing activity  |2 nationallicence 
690 7 |a liver injury  |2 nationallicence 
690 7 |a offspring  |2 nationallicence 
700 1 |a Bryukhin  |D G.  |u South Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia  |4 aut 
700 1 |a Shopova  |D A.  |u Chelyabinsk State University, Chelyabinsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/4(2015-08-01), 435-437  |x 0007-4888  |q 159:4<435  |1 2015  |2 159  |o 10517 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bryukhin  |D G.  |u South Ural State Medical University, Ministry of Health of the Russian Federation, Chelyabinsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Shopova  |D A.  |u Chelyabinsk State University, Chelyabinsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/4(2015-08-01), 435-437  |x 0007-4888  |q 159:4<435  |1 2015  |2 159  |o 10517