caa a22 4500 605536104 CHVBK 20210128100850.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s10517-015-3033-3 doi (NATIONALLICENCE)springer-10.1007/s10517-015-3033-3 Effect of Heparin on Contractile Activity of Lymph Node Capsule [Elektronische Daten] [M. Pan'kova, G. Lobov] Experiments on smooth muscle strips isolated from the capsule of bovine mesenteric lymph node showed that heparin low concentrations (0.010-0.025 U/ml) stimulating spontaneous isometric phasic contractions of smooth muscles, but higher heparin concentrations reduced or even completely eliminated these contractions. The inhibitory effects of heparin were presumably realized via stimulation of NO production by endothelial cells of the subcapsular space followed by activation of ATP-sensitive potassium channels of capsular myocytes and via modulation of prostaglandin synthesis. Springer Science+Business Media New York, 2015 lymph nodes nationallicence smooth muscles nationallicence endotheliocytes nationallicence contractility nationallicence heparin nationallicence Pan'kova M. Laboratory of Cardiovascular and Lymph System Physiology, I. P. Pavlov Institute of Physiology, the Russian Academy of Sciences, St. Petersburg, Russia aut Lobov G. Laboratory of Cardiovascular and Lymph System Physiology, I. P. Pavlov Institute of Physiology, the Russian Academy of Sciences, St. Petersburg, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/5(2015-09-01), 632-634 0007-4888 159:5<632 2015 159 10517 https://doi.org/10.1007/s10517-015-3033-3 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3033-3 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pan'kova M. Laboratory of Cardiovascular and Lymph System Physiology, I. P. Pavlov Institute of Physiology, the Russian Academy of Sciences, St. Petersburg, Russia aut NATIONALLICENCE 700 1- Lobov G. Laboratory of Cardiovascular and Lymph System Physiology, I. P. Pavlov Institute of Physiology, the Russian Academy of Sciences, St. Petersburg, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/5(2015-09-01), 632-634 0007-4888 159:5<632 2015 159 10517