LPO-Antioxidant Defense System in Newborns and Women Drinking Small Amounts of Alcohol During Pregnancy

Verfasser / Beitragende:
[L. Kolesnikova, N. Protopopova, S. Kolesnikov, A. Maryanyan, B. Vlasov, L. Natyaganova]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/5(2015-09-01), 594-596
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-3021-7  |2 doi 
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245 0 0 |a LPO-Antioxidant Defense System in Newborns and Women Drinking Small Amounts of Alcohol During Pregnancy  |h [Elektronische Daten]  |c [L. Kolesnikova, N. Protopopova, S. Kolesnikov, A. Maryanyan, B. Vlasov, L. Natyaganova] 
520 3 |a We studied the effects of consumption of low-alcohol drinks (no more than 2 doses) during pregnancy on the state of LPO-antioxidant defense system and glutathione level in the blood serum and erythrocytes of pregnant women and newborns. It was found that even single alcohol intake was followed by the development of oxidative stress in women and newborns. In pregnant women, the decrease in reduced glutathione content and glutathione reductase activity associated with increased level of oxidized glutathione and glutathione transferase activity were typical changes. In newborns, the decrease in reduced glutathione concentration was accompanied by a decrease in glutathione reductase, glutathione transferase, and glutathione peroxidase activities. It should be emphasized that even small alcohol doses produce delayed negative effects on metabolism of the mother and newborns. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a state of system of lipid peroxidation-antioxidant defense  |2 nationallicence 
690 7 |a glutathione  |2 nationallicence 
690 7 |a pregnant women  |2 nationallicence 
690 7 |a newborns  |2 nationallicence 
690 7 |a alcohol drinks  |2 nationallicence 
700 1 |a Kolesnikova  |D L.  |u Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia  |4 aut 
700 1 |a Protopopova  |D N.  |u Irkutsk State Medical Academy of Postgraduate Education, Irkutsk, Russia  |4 aut 
700 1 |a Kolesnikov  |D S.  |u Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia  |4 aut 
700 1 |a Maryanyan  |D A.  |u Irkutsk State Medical University of the Ministry of Health of the Russian Federation, Irkutsk, Russia  |4 aut 
700 1 |a Vlasov  |D B.  |u Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia  |4 aut 
700 1 |a Natyaganova  |D L.  |u Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/5(2015-09-01), 594-596  |x 0007-4888  |q 159:5<594  |1 2015  |2 159  |o 10517 
856 4 0 |u https://doi.org/10.1007/s10517-015-3021-7  |q text/html  |z Onlinezugriff via DOI 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kolesnikova  |D L.  |u Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Protopopova  |D N.  |u Irkutsk State Medical Academy of Postgraduate Education, Irkutsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kolesnikov  |D S.  |u Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Maryanyan  |D A.  |u Irkutsk State Medical University of the Ministry of Health of the Russian Federation, Irkutsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Vlasov  |D B.  |u Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Natyaganova  |D L.  |u Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/5(2015-09-01), 594-596  |x 0007-4888  |q 159:5<594  |1 2015  |2 159  |o 10517