caa a22 4500 60553621X CHVBK 20210128100851.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s10517-015-3021-7 doi (NATIONALLICENCE)springer-10.1007/s10517-015-3021-7 LPO-Antioxidant Defense System in Newborns and Women Drinking Small Amounts of Alcohol During Pregnancy [Elektronische Daten] [L. Kolesnikova, N. Protopopova, S. Kolesnikov, A. Maryanyan, B. Vlasov, L. Natyaganova] We studied the effects of consumption of low-alcohol drinks (no more than 2 doses) during pregnancy on the state of LPO-antioxidant defense system and glutathione level in the blood serum and erythrocytes of pregnant women and newborns. It was found that even single alcohol intake was followed by the development of oxidative stress in women and newborns. In pregnant women, the decrease in reduced glutathione content and glutathione reductase activity associated with increased level of oxidized glutathione and glutathione transferase activity were typical changes. In newborns, the decrease in reduced glutathione concentration was accompanied by a decrease in glutathione reductase, glutathione transferase, and glutathione peroxidase activities. It should be emphasized that even small alcohol doses produce delayed negative effects on metabolism of the mother and newborns. Springer Science+Business Media New York, 2015 state of system of lipid peroxidation-antioxidant defense nationallicence glutathione nationallicence pregnant women nationallicence newborns nationallicence alcohol drinks nationallicence Kolesnikova L. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia aut Protopopova N. Irkutsk State Medical Academy of Postgraduate Education, Irkutsk, Russia aut Kolesnikov S. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia aut Maryanyan A. Irkutsk State Medical University of the Ministry of Health of the Russian Federation, Irkutsk, Russia aut Vlasov B. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia aut Natyaganova L. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/5(2015-09-01), 594-596 0007-4888 159:5<594 2015 159 10517 https://doi.org/10.1007/s10517-015-3021-7 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3021-7 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kolesnikova L. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia aut NATIONALLICENCE 700 1- Protopopova N. Irkutsk State Medical Academy of Postgraduate Education, Irkutsk, Russia aut NATIONALLICENCE 700 1- Kolesnikov S. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia aut NATIONALLICENCE 700 1- Maryanyan A. Irkutsk State Medical University of the Ministry of Health of the Russian Federation, Irkutsk, Russia aut NATIONALLICENCE 700 1- Vlasov B. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia aut NATIONALLICENCE 700 1- Natyaganova L. Research Center of Family Health and Human Reproduction Problems, Irkutsk, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/5(2015-09-01), 594-596 0007-4888 159:5<594 2015 159 10517