Effects of a New Benzimidazole Derivative on Generative Function of Female Rats
Gespeichert in:
Verfasser / Beitragende:
[E. Kuzubova, L. Bugaeva, S. Sergeeva, V. Petrov, V. Kataev, I. Kharlamov, M. Mal'tsev]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/5(2015-09-01), 635-637
Format:
Artikel (online)
Online Zugang:
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3034-2 |2 doi |
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| 245 | 0 | 0 | |a Effects of a New Benzimidazole Derivative on Generative Function of Female Rats |h [Elektronische Daten] |c [E. Kuzubova, L. Bugaeva, S. Sergeeva, V. Petrov, V. Kataev, I. Kharlamov, M. Mal'tsev] |
| 520 | 3 | |a The effects of a new thietanylbenzimidazole derivative (K-134) on estrous cycles, conception processes, and sexual behavior of female rats were studied. Two-week oral treatment with K-134 in doses of 5 and 50 mg/kg shortened the estrus phase and prolonged proestrus. Changes in sexual behavior were presented by activation of receptive sexual motivations without affecting proceptive motivations. The pregnancy and fertility indexes in experimental females after mating with intact males increased and pre- and postimplantation embryonic death decreased. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a benzimidazole derivatives |2 nationallicence | |
| 690 | 7 | |a actoprotectors |2 nationallicence | |
| 690 | 7 | |a reproductivity |2 nationallicence | |
| 690 | 7 | |a sexual behavior |2 nationallicence | |
| 690 | 7 | |a estrous cycle |2 nationallicence | |
| 700 | 1 | |a Kuzubova |D E. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Bugaeva |D L. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Sergeeva |D S. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Petrov |D V. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Kataev |D V. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Kharlamov |D I. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Mal'tsev |D M. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/5(2015-09-01), 635-637 |x 0007-4888 |q 159:5<635 |1 2015 |2 159 |o 10517 | |
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| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuzubova |D E. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Bugaeva |D L. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Sergeeva |D S. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Petrov |D V. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kataev |D V. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kharlamov |D I. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Mal'tsev |D M. |u Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/5(2015-09-01), 635-637 |x 0007-4888 |q 159:5<635 |1 2015 |2 159 |o 10517 | ||