caa a22 4500 605536228 CHVBK 20210128100851.0 cr unu---uuuuu 210128e20150901xx s 000 0 eng 10.1007/s10517-015-3034-2 doi (NATIONALLICENCE)springer-10.1007/s10517-015-3034-2 Effects of a New Benzimidazole Derivative on Generative Function of Female Rats [Elektronische Daten] [E. Kuzubova, L. Bugaeva, S. Sergeeva, V. Petrov, V. Kataev, I. Kharlamov, M. Mal'tsev] The effects of a new thietanylbenzimidazole derivative (K-134) on estrous cycles, conception processes, and sexual behavior of female rats were studied. Two-week oral treatment with K-134 in doses of 5 and 50 mg/kg shortened the estrus phase and prolonged proestrus. Changes in sexual behavior were presented by activation of receptive sexual motivations without affecting proceptive motivations. The pregnancy and fertility indexes in experimental females after mating with intact males increased and pre- and postimplantation embryonic death decreased. Springer Science+Business Media New York, 2015 benzimidazole derivatives nationallicence actoprotectors nationallicence reproductivity nationallicence sexual behavior nationallicence estrous cycle nationallicence Kuzubova E. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut Bugaeva L. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut Sergeeva S. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut Petrov V. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut Kataev V. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut Kharlamov I. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut Mal'tsev M. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/5(2015-09-01), 635-637 0007-4888 159:5<635 2015 159 10517 https://doi.org/10.1007/s10517-015-3034-2 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-3034-2 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Kuzubova E. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut NATIONALLICENCE 700 1- Bugaeva L. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut NATIONALLICENCE 700 1- Sergeeva S. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut NATIONALLICENCE 700 1- Petrov V. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut NATIONALLICENCE 700 1- Kataev V. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut NATIONALLICENCE 700 1- Kharlamov I. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut NATIONALLICENCE 700 1- Mal'tsev M. Research Institute of Pharmacology, Volgograd State Medical University, Volgograd, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/5(2015-09-01), 635-637 0007-4888 159:5<635 2015 159 10517