Thymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats

Verfasser / Beitragende:
[A. Novoseletskaya, N. Kiseleva, I. Zimina, O. Bystrova, O. Belova, A. Inozemtsev, V. Arion, V. Sergienko]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/5(2015-09-01), 623-625
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-3030-6  |2 doi 
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245 0 0 |a Thymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats  |h [Elektronische Daten]  |c [A. Novoseletskaya, N. Kiseleva, I. Zimina, O. Bystrova, O. Belova, A. Inozemtsev, V. Arion, V. Sergienko] 
520 3 |a We studied the effects of tactivin and splenic polypeptides on learning and memory of thymectomized animals. In 3-week rats, thymectomy blocked active avoidance conditioning. Injections of tactivin (0.5 mg/kg) during 1 month after surgery restored learning capacity; splenic polypeptides were ineffective. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a thymus  |2 nationallicence 
690 7 |a thymectomy  |2 nationallicence 
690 7 |a learning  |2 nationallicence 
690 7 |a memory  |2 nationallicence 
700 1 |a Novoseletskaya  |D A.  |u Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov, Moscow State University, Moscow, Russia  |4 aut 
700 1 |a Kiseleva  |D N.  |u Department of Pharmacology,Pediatric Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
700 1 |a Zimina  |D I.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
700 1 |a Bystrova  |D O.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
700 1 |a Belova  |D O.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
700 1 |a Inozemtsev  |D A.  |u Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov, Moscow State University, Moscow, Russia  |4 aut 
700 1 |a Arion  |D V.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
700 1 |a Sergienko  |D V.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/5(2015-09-01), 623-625  |x 0007-4888  |q 159:5<623  |1 2015  |2 159  |o 10517 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Novoseletskaya  |D A.  |u Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov, Moscow State University, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kiseleva  |D N.  |u Department of Pharmacology,Pediatric Faculty, N. I. Pirogov Russian National Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Zimina  |D I.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Bystrova  |D O.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Belova  |D O.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Inozemtsev  |D A.  |u Department of Higher Nervous Activity, Biological Faculty, M. V. Lomonosov, Moscow State University, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Arion  |D V.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Sergienko  |D V.  |u Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/5(2015-09-01), 623-625  |x 0007-4888  |q 159:5<623  |1 2015  |2 159  |o 10517