Effect of Sulfated Polysaccharides from Brown Algae on Apoptosis of Human Peripheral Blood Lymphocytes
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| 024 | 7 | 0 | |a 10.1007/s10517-015-3028-0 |2 doi |
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| 245 | 0 | 0 | |a Effect of Sulfated Polysaccharides from Brown Algae on Apoptosis of Human Peripheral Blood Lymphocytes |h [Elektronische Daten] |c [A. Gazha, T. Zaporozhets, T. Kuznetsova, T. Zvyaguintseva, N. Besednova] |
| 520 | 3 | |a We studied the influence of fucoidans from brown algae Fucus evanescens, Laminaria cichorioides and Laminaria japonica on apoptosis of human peripheral blood lymphocytes. It was demonstrated that fucoidans induced lymphocyte apoptosis, increased the proportion of cells with low mitochondrial transmembrane potential, and inhibit expression of Bcl-xL gene in blood lymphocytes. These findings suggest that lymphocyte apoptosis induced by the analyzed sulfated polysaccharides is mediated by mitochondrial pathway. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a apoptosis |2 nationallicence | |
| 690 | 7 | |a periperal blood lymphocytes |2 nationallicence | |
| 690 | 7 | |a mitochondrial membrane potential |2 nationallicence | |
| 690 | 7 | |a fucoidan |2 nationallicence | |
| 700 | 1 | |a Gazha |D A. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Zaporozhets |D T. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Kuznetsova |D T. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Zvyaguintseva |D T. |u G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | |
| 700 | 1 | |a Besednova |D N. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/5(2015-09-01), 617-619 |x 0007-4888 |q 159:5<617 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-3028-0 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-3028-0 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Gazha |D A. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zaporozhets |D T. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuznetsova |D T. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Zvyaguintseva |D T. |u G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Besednova |D N. |u G. P. Somov Research Institute of Epidemiology and Microbiology, Siberian Division of the Russian Academy of Sciences, Vladivostok, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/5(2015-09-01), 617-619 |x 0007-4888 |q 159:5<617 |1 2015 |2 159 |o 10517 | ||