Effect of Sodium Nitrite and L-NNA on the Outcome of Experimental Ischemic Stroke
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2926-5 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2926-5 | ||
| 245 | 0 | 0 | |a Effect of Sodium Nitrite and L-NNA on the Outcome of Experimental Ischemic Stroke |h [Elektronische Daten] |c [V. Kuzenkov, A. Krushinskii] |
| 520 | 3 | |a We studied the effect of sodium nitrite in doses of 5 and 50 mg/kg and NO synthase inhibitor L-NNA in a dose of 20 mg/kg on the course of experimental ischemic stroke caused by occlusion of both carotid arteries. Sodium nitrite and NO synthase inhibitor were administered 1 h prior to occlusion of еру carotid arteries and 5 sec after brain ischemia. Sodium nitrite in a dose of 5 mg/kg had a protective effect on the time course of neurological disorders and reduced animal mortality. NO synthase inhibitor L-NNA aggravated the neurological symptoms. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a brain ischemia |2 nationallicence | |
| 690 | 7 | |a sodium nitrite |2 nationallicence | |
| 690 | 7 | |a NO-synthase |2 nationallicence | |
| 690 | 7 | |a neurological disorders |2 nationallicence | |
| 700 | 1 | |a Kuzenkov |D V. |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Krushinskii |D A. |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 217-220 |x 0007-4888 |q 159:2<217 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2926-5 |q text/html |z Onlinezugriff via DOI |
| 898 | |a BK010053 |b XK010053 |c XK010000 | ||
| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2926-5 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuzenkov |D V. |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Krushinskii |D A. |u Biological Faculty, M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 217-220 |x 0007-4888 |q 159:2<217 |1 2015 |2 159 |o 10517 | ||