Role of Purinergic Receptors of Erythrocytes in the Regulation of Conformation and Oxygen- and NO-Transporting Capacity of Hemoglobin
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2925-6 |2 doi |
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| 245 | 0 | 0 | |a Role of Purinergic Receptors of Erythrocytes in the Regulation of Conformation and Oxygen- and NO-Transporting Capacity of Hemoglobin |h [Elektronische Daten] |c [S. Kovalenko, A. Yusipovich, E. Parshina, G. Maksimov] |
| 520 | 3 | |a Raman spectroscopy was used to investigate changes in hemoglobin conformation and its ability to transfer O2 and NO induced by activation of purinergic receptors of erythrocytes with extracellular ATP. It was found that addition of ATP in a final concentration of 0.1 mM and higher to erythrocyte suspension was followed by changes in hematoporphyrin conformation, while addition of ATP in a concentration of 1 mM and higher increased the proportion of oxyhemoglobin and NO-associated hemoglobin complexes. In case of purinergic receptors activation in blood erythrocytes, significant changes in hemoglobin conformation were observed only at a final ATP concentration of 5 mM, probably due to buffer properties of the blood. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a ATP |2 nationallicence | |
| 690 | 7 | |a hemoglobin |2 nationallicence | |
| 690 | 7 | |a erythrocytes |2 nationallicence | |
| 690 | 7 | |a Raman spectroscopy |2 nationallicence | |
| 690 | 7 | |a purinergic receptors |2 nationallicence | |
| 700 | 1 | |a Kovalenko |D S. |u M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Yusipovich |D A. |u M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Parshina |D E. |u M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | |
| 700 | 1 | |a Maksimov |D G. |u M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 213-216 |x 0007-4888 |q 159:2<213 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2925-6 |q text/html |z Onlinezugriff via DOI |
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| 900 | 7 | |a Metadata rights reserved |b Springer special CC-BY-NC licence |2 nationallicence | |
| 908 | |D 1 |a research-article |2 jats | ||
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| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2925-6 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kovalenko |D S. |u M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Yusipovich |D A. |u M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Parshina |D E. |u M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Maksimov |D G. |u M. V. Lomonosov Moscow State University, Moscow, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 213-216 |x 0007-4888 |q 159:2<213 |1 2015 |2 159 |o 10517 | ||