Pharmacokinetic Properties of a New Glutamic Acid Derivative Glutaron
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| 024 | 7 | 0 | |a 10.1007/s10517-015-2929-2 |2 doi |
| 035 | |a (NATIONALLICENCE)springer-10.1007/s10517-015-2929-2 | ||
| 245 | 0 | 0 | |a Pharmacokinetic Properties of a New Glutamic Acid Derivative Glutaron |h [Elektronische Daten] |c [L. Smirnova, A. Ryabukha, K. Kuznetsov, E. Suchkov, V. Perfilova, I. Tyurenkov] |
| 520 | 3 | |a Inhomogenous distribution of glutaron in organs and tissues was found after intravenous and peroral administration: the agent demonstrated high affi nity to organs with high degree of vascularization (lungs and heart) and elimination (kidney). Glutaron easily penetrates through the blood-brain barrier, which is consistent with its concentration in the adipose tissue. | |
| 540 | |a Springer Science+Business Media New York, 2015 | ||
| 690 | 7 | |a derivatives of glutamic acid |2 nationallicence | |
| 690 | 7 | |a pharmacokinetics |2 nationallicence | |
| 690 | 7 | |a tissue bioavailability |2 nationallicence | |
| 690 | 7 | |a glutaron |2 nationallicence | |
| 700 | 1 | |a Smirnova |D L. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Ryabukha |D A. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Kuznetsov |D K. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Suchkov |D E. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Perfilova |D V. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 700 | 1 | |a Tyurenkov |D I. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | |
| 773 | 0 | |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 229-231 |x 0007-4888 |q 159:2<229 |1 2015 |2 159 |o 10517 | |
| 856 | 4 | 0 | |u https://doi.org/10.1007/s10517-015-2929-2 |q text/html |z Onlinezugriff via DOI |
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| 908 | |D 1 |a research-article |2 jats | ||
| 949 | |B NATIONALLICENCE |F NATIONALLICENCE |b NL-springer | ||
| 950 | |B NATIONALLICENCE |P 856 |E 40 |u https://doi.org/10.1007/s10517-015-2929-2 |q text/html |z Onlinezugriff via DOI | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Smirnova |D L. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Ryabukha |D A. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Kuznetsov |D K. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Suchkov |D E. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Perfilova |D V. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 700 |E 1- |a Tyurenkov |D I. |u Laboratory of Pharmacological Kinetics, Department of Pharmacology and Biopharmaceutics of the Faculty of Continuing Medical Education, Volgograd State Medical University, Volgograd, Russia |4 aut | ||
| 950 | |B NATIONALLICENCE |P 773 |E 0- |t Bulletin of Experimental Biology and Medicine |d Springer US; http://www.springer-ny.com |g 159/2(2015-06-01), 229-231 |x 0007-4888 |q 159:2<229 |1 2015 |2 159 |o 10517 | ||