caa a22 4500 605536597 CHVBK 20210128100853.0 cr unu---uuuuu 210128e20150601xx s 000 0 eng 10.1007/s10517-015-2923-8 doi (NATIONALLICENCE)springer-10.1007/s10517-015-2923-8 Global Tests in Evaluation of the Function of Proand Anticoagulant Systems: Present and Future [Elektronische Daten] [V. Udut, I. Tyutrin, M. Solov'ev, V. Klimenkova, E. Malyugin, O. Karchagina, E. Borodulina, A. Turenko] Comparative analysis of the effectiveness of global tests for evaluation of the blood coagulation systems demonstrated the possibility of obtaining express data on hemostasis stages I-II and III when working with native substrate (whole blood). Changes in viscous characteristics of the whole blood recorded ex vivo during hemocoagulation allowed us to propose the concept of permanency of fibrinogenesis as the obligatory in vivo process determining the hemostatic potential, an integral characteristic of the hemocoagulation cycle providing sufficient blood fluidity and limiting extravasation of blood components under conditions of permeability disturbances and damage to the vascular wall. Springer Science+Business Media New York, 2015 hemocoagulation nationallicence hemostatic potential nationallicence whole blood nationallicence global tests nationallicence low-frequency piezoelectric thromboelastography nationallicence Udut V. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Tyutrin I. Mednord-Tekhnika, Tomsk, Russia aut Solov'ev M. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Klimenkova V. Mednord-Tekhnika, Tomsk, Russia aut Malyugin E. Mednord-Tekhnika, Tomsk, Russia aut Karchagina O. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Borodulina E. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut Turenko A. Mednord-Tekhnika, Tomsk, Russia aut Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/2(2015-06-01), 205-208 0007-4888 159:2<205 2015 159 10517 https://doi.org/10.1007/s10517-015-2923-8 text/html Onlinezugriff via DOI BK010053 XK010053 XK010000 Metadata rights reserved Springer special CC-BY-NC licence nationallicence 1 research-article jats NATIONALLICENCE NATIONALLICENCE NL-springer NATIONALLICENCE 856 40 https://doi.org/10.1007/s10517-015-2923-8 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Udut V. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Tyutrin I. Mednord-Tekhnika, Tomsk, Russia aut NATIONALLICENCE 700 1- Solov'ev M. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Klimenkova V. Mednord-Tekhnika, Tomsk, Russia aut NATIONALLICENCE 700 1- Malyugin E. Mednord-Tekhnika, Tomsk, Russia aut NATIONALLICENCE 700 1- Karchagina O. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Borodulina E. E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia aut NATIONALLICENCE 700 1- Turenko A. Mednord-Tekhnika, Tomsk, Russia aut NATIONALLICENCE 773 0- Bulletin of Experimental Biology and Medicine Springer US; http://www.springer-ny.com 159/2(2015-06-01), 205-208 0007-4888 159:2<205 2015 159 10517