Cell-Mediated Hemolytic Activity of Nosocomial Pseudomonas Aeruginosa Strains

Verfasser / Beitragende:
[M. Kuznetsova, T. Karpunina]
Ort, Verlag, Jahr:
2015
Enthalten in:
Bulletin of Experimental Biology and Medicine, 159/2(2015-06-01), 258-261
Format:
Artikel (online)
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024 7 0 |a 10.1007/s10517-015-2936-3  |2 doi 
035 |a (NATIONALLICENCE)springer-10.1007/s10517-015-2936-3 
245 0 0 |a Cell-Mediated Hemolytic Activity of Nosocomial Pseudomonas Aeruginosa Strains  |h [Elektronische Daten]  |c [M. Kuznetsova, T. Karpunina] 
520 3 |a Cell-mediated hemolysis and adhesion index of nosocomial P. aeruginosa strains were experimentally studied. The highest hemoglobin release was recorded after centrifugation of erythrocyte and bacterial cell suspension preincubated at 37C. All cultures were referred to highly adherent variants. The relationship between P. aeruginosa adhesion activity and erythrocyte lysis was found only in "passive” cell-cell contact. No correlation between cellassociated hemolysis and hemolysis caused by secreted factors was detected. It seems that the cytotoxicity of the studied P. aeruginosa strains was determined by ExoU and ExoS third type secretion effectors. 
540 |a Springer Science+Business Media New York, 2015 
690 7 |a P. aeruginosa  |2 nationallicence 
690 7 |a cell-mediated hemolysis  |2 nationallicence 
690 7 |a adhesion  |2 nationallicence 
690 7 |a ExoU  |2 nationallicence 
690 7 |a ExoS  |2 nationallicence 
700 1 |a Kuznetsova  |D M.  |u Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm, Russia  |4 aut 
700 1 |a Karpunina  |D T.  |u E. A. Wagner Perm State Medical Academy, Ministry of Health of the Russian Federation, Perm, Russia  |4 aut 
773 0 |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/2(2015-06-01), 258-261  |x 0007-4888  |q 159:2<258  |1 2015  |2 159  |o 10517 
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950 |B NATIONALLICENCE  |P 700  |E 1-  |a Kuznetsova  |D M.  |u Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences, Perm, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 700  |E 1-  |a Karpunina  |D T.  |u E. A. Wagner Perm State Medical Academy, Ministry of Health of the Russian Federation, Perm, Russia  |4 aut 
950 |B NATIONALLICENCE  |P 773  |E 0-  |t Bulletin of Experimental Biology and Medicine  |d Springer US; http://www.springer-ny.com  |g 159/2(2015-06-01), 258-261  |x 0007-4888  |q 159:2<258  |1 2015  |2 159  |o 10517